Human papilloma virus (HPV) is present in greater than 90% of cervical cancers. HPV encodes two proteins, E6 and E7, that are potent contributors to cancer development. E7 disables RB; E6 binds to p53 and targets it for degradation. Discuss how E6 and E7 might contribute to the development of the cancerous state in infected cells.
Human papilloma virus (HPV) is present in greater than 90% of cervical cancers. HPV encodes two proteins, E6 and E7, that are potent contributors to cancer development. E7 disables RB; E6 binds to p53 and targets it for degradation. Discuss how E6 and E7 might contribute to the development of the cancerous state in infected cells.
Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter42: Animal Development
Section: Chapter Questions
Problem 3CT
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