True or false: F1 unit of ATP synthase is capable of synthesizing 3ATP molecules per a complete revolution. F1 unit can synthesize 4 or 5ATP molecules if the c subunit of F0 unit has more than 12 proton binding peptides. Unlike Complex I inhibitors, Complex IV inhibitors can shut down the entire ETC.
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True or false:
F1 unit of ATP synthase is capable of synthesizing 3ATP molecules per a complete revolution. F1 unit can synthesize 4 or 5ATP molecules if the c subunit of F0 unit has more than 12 proton binding peptides.
Unlike Complex I inhibitors, Complex IV inhibitors can shut down the entire ETC.
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- "Anaerobic glycolysis" (the conversion of glucose all the way to two lactate molecules) results in no net production of NADH. True or False- whyEnzymes normally enhance the rates of biochemical reactions by preferentially binding and stabilizing the transition states rather than either the substrates or the products of a reaction. The F|-subunit of ATP synthase does not fit this norm so well as tight binding to ATP rather than a transition state is employed to make ATP. Explain the binding-change model of the mechanism of ATP-synthase. How and why is the proton-motive force used in the reaction cycle of ATP synthase?The proton-motive force drives the rotation of the Y subunit of ATP synthase. This creates conformational changes in the active sites of ATP synthase that accelerate the rate of bond formation between ADP and P, through the stabilization of a tetrahedral intermediate. True False
- True or false? The E2 component of the Pyruvate Dehydrogenase complex binds NAD+ in its active site.Assuming a eukaryotic cell has complete metabolic ability to fully oxidize glucose(including all metabolic pathways ane necessary organelles).At biochemical level explain the consequence of low oxygen content on all aspects of energy production associated with glucose catabolism.All steps in the calculations must be reported, incomplete reporting of these leads directly to return. Make a theoretical calculation of how many ATP molecules can be formed from the degradation of an acetyl-CoA molecule to carbon dioxide and water if the entire proton gradient across the mitochondria's inner membrane can be used for ATP production and when the ATP synthase has 15 c-subunits.
- Why palmitate molecule generated a total of 129 ATPs for complete oxidation? compute the ATP molecules generated in the complete oxidation of other fatty acids.a) Metabolic process in which hexose metabolism occurs? Amount of steps? Since this metabolic process (hexose -> 2 pyruvate) is exergonic. b) But, looking at the individual reactions that makeup this process, they are a combination of exergonic and endergonic reactions. (true or false). If false, explain why. If true explain the contribution of endergonic reactions to the overall exergonic process.assuming each NADH produces 3 ATP and each fadh2 produces 2 ATP in oxidative phosphorylation (perfect world scenario), how many ATP molecules can one glucose molecule make via cellular respiration under aerobic conditions?
- true/false: The cofactor ATP is essential in all transamination reactions.The regulation of 1-phosphofructokinase occurs primarily by allosteric effectors, including ATP and ADP. Given that phosphofructokinase activity is necessary for glycolysis to proceed, predict what effect ATP would have. How about ADP?True or False In the presence of enzymes, the value of free energy of activiation (delta G°‡) for the reaction is more likely to become negative.