Which of the following is not a mechanism of regulating the complement pathway?O a. C1 esterase inhibitor dissociation of C1q from C1r2s2b.prevention of C3 convertase assembly by C3 convertase regulatory protein.c. Factor H binding to C3b preventing its association with factor Bd. Formation of the membrane attack complex by the association of C9 protein subunits. Sudden death due to shock following exposure to ingested or injected antigen is considered aO a. Type Ib. Type IIOC Type IIId. Type IVhy

It is an enhancement of immune response. It plays an important role in innate and adaptive immunity.…

Answered: ttack complex by the association of C9…

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ttack complex by the association of C9 protein subunits.

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter34: Immunity

Section: Chapter Questions

Problem 3SA: Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b....

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Question

Which of the following is not a mechanism of regulating the complement pathway?
O a. C1 esterase inhibitor dissociation of C1q from C1r2s2
b.prevention of C3 convertase assembly by C3 convertase regulatory protein.
c. Factor H binding to C3b preventing its association with factor B
d. Formation of the membrane attack complex by the association of C9 protein subunits.

Sudden death due to shock following exposure to ingested or injected antigen is considered a
O a. Type I
b. Type II
OC Type III
d. Type IV
hy

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If a series of genetic mutations prevented some, but not all, of the complement proteins from binding antibodies or pathogens, would the entire complement system be compromised?
Complement proteins function in defense by _______. a. neutralizing toxins b. enhancing resident bacteria c. promoting inflammation d. forming pores that cause pathogens to disintegrate e. both a and b f. both c and d
Activated complement proteins ________. a. puncture cells c. attract macrophages b. promote inflammation d. all of the above
The Complement System Kills Microorganisms The complement system supplements the inflammatory response by directly killing microorganisms. Describe the life cycle of complement proteins, from their synthesis in the liver to their activity at the site of an infection.
Which of the following does not describe the outcome of complement activation? a. chemotaxis b. opsonization c. vasoconstriction d. proteolysis e. membrane permeabilization.
A(n) _____ is an inactive form of an enzyme that frequently participates in a cascade of enzymatic reactions during complement activation. a. regulator of complement activation b. convertase c. complement control protein module d. zymogen e. opsonin.
Which of the following does not accurately describe complement components? A. made by the spleen B. located in extracellular spaces C. some function as proteases once activated D. activated by a cascade of enzymatic reactions. E. soluble proteins
Which of these statements about complement proteins C3a and C5a is false?a. They are released during the complement fixation process.b. They stimulate chemotaxis of phagocytic cells.c. They promote the activity of phagocytic cells.d.They produce pores in the victim plasma membrane.
Which of the following is the end product of the complement system?a. properdin b. cascade reaction c. membrane attack complex d. complement factor C9
Which of the following is not true about the complementsystem?(a) It is a set of more than 20 proteins that play a key rolein host defense by specifically acting in different waystoward different microorganisms.(b) Its general functions include enhancing phagocytosis byphagocytes, lysing microbes and enveloped viruses directly, and generating peptide fragments that regulateinflammation and immune responses.(c) It is a fast-acting innate host defense that works in a cascade.(d) There are three pathways classical, lectin, and alternative.(e) The effects of each activation pathways are the same.
Explain why each choice (a-d) is correct or incorrect. All of the following are true of the classical pathway of complement activation EXCEPT one. Select the one answer that does NOT describe the classical pathway of complement activation. a. It is an example of overlap between innate and adaptive immune function. b. It requires that circulating antibodies are bound to antigens. c. Classical activation will result in enhanced inflammation, opsonization as well as formation of MAC proteins. d. It activates T helper cells by presenting antigen to them.
Ingestion of complement-tagged pathogens by phagocytes is mediated by receptors for the bound complement proteins. Even when the complement cascade fails to proceed beyond generating the C3 convertase, complement activation is effective at inducing pathogen uptake and destruction. This process of immune protection is mediated by: Activation of complement inhibitory receptors on phagocytes that promote pathogen uptake Activation of soluble proteases in the serum that disrupt pathogen membranes Engagement of complement receptors on phagocytes by C3b and its cleavage products which promotes phagocytosis Engagement of complement receptors on B cells that promotes antibody production Stimulation of antimicrobial peptide secretion by phagocytes