Vasopressin or antidiuretic hormone (ADH) is a peptide hormone synthesize nypothalamus. This hormone, when present, induces expression of water transpor aquaporins) in the late distal tubule and collecting duct of the kidney to increase w reabsorption. Binding to the receptor triggers an intracellular cyclic adenosine monophosphate (CAMP) pathway. Arrange the following steps of hormone signalling in the proper order by putting 1, n the space provided. CAMP activates CAMP-dependent protein kinase (PKA). Recruitment of inactive G-protein made of heterotrimeric subunits which has GDP bound to a-subunit. Conformation change in GPCR. Adenylyl cyclase converts ATP into CAMP. PKA phosphorylates proteins in the cell. A cellular response is seen in the cell. a-subunit with GTP bound activates adenylyl cyclase. Activation of G-protein, thus GDP released an GTP binds to a-subunit. x-subunit of G-protein dissociates from By-dimer. Hormone binding to its G-protein coupled receptor (GPCR). ncrease in CAMP concentration, which is the second messenger.
Vasopressin or antidiuretic hormone (ADH) is a peptide hormone synthesize nypothalamus. This hormone, when present, induces expression of water transpor aquaporins) in the late distal tubule and collecting duct of the kidney to increase w reabsorption. Binding to the receptor triggers an intracellular cyclic adenosine monophosphate (CAMP) pathway. Arrange the following steps of hormone signalling in the proper order by putting 1, n the space provided. CAMP activates CAMP-dependent protein kinase (PKA). Recruitment of inactive G-protein made of heterotrimeric subunits which has GDP bound to a-subunit. Conformation change in GPCR. Adenylyl cyclase converts ATP into CAMP. PKA phosphorylates proteins in the cell. A cellular response is seen in the cell. a-subunit with GTP bound activates adenylyl cyclase. Activation of G-protein, thus GDP released an GTP binds to a-subunit. x-subunit of G-protein dissociates from By-dimer. Hormone binding to its G-protein coupled receptor (GPCR). ncrease in CAMP concentration, which is the second messenger.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 18RE
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Transcribed Image Text:Vasopressin or antidiuretic hormone (ADH) is a peptide hormone synthesized in the
a)
hypothalamus. This hormone, when present, induces expression of water transport proteins
(aquaporins) in the late distal tubule and collecting duct of the kidney to increase water
reabsorption. Binding to the receptor triggers an intracellular cyclic adenosine
monophosphate (CAMP) pathway.
Arrange the following steps of hormone signalling in the proper order by putting 1, 2, 3, etc
in the space provided,
CAMP activates CAMP-dependent protein kinase (PKA).
Recruitment of inactive G-protein made of heterotrimeric subunits which has
GDP bound to a-subunit.
Conformation change in GPCR.
Adenylyl cyclase converts ATP into CAMP.
PKA phosphorylates proteins in the cell.
A cellular response is seen in the cell.
a-subunit with GTP bound activates adenylyl cyclase.
Activation of G-protein, thus GDP released an GTP binds to a-subunit.
a-subunit of G-protein dissociates from By-dimer.
Hormone binding to its G-protein coupled receptor (GPCR).
Increase in CAMP concentration, which is the second messenger.
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