What is ER-positive breast cancer causes the clinicians to use aromatase inhibitors? Why are aromatase inhibitors good for breast cancer er positive in elder women? Explain in detail
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- Explain in detail how an ER-positive breast cancer be treated with aromatase inhibitors?Can a 65-year-old woman with ER-positive breast cancer be treated with aromatase inhibitors? Explain your answer in detailHydroxyurea has been shown to increase the expression of fetal hemoglobin in adult red blood cells, by a mechanism that remains unclear. Explain why hydroxyurea can be a useful therapy for patients with sickle-cell anemia.
- why might bodybuilders take aromatase inhibitors?Hemophilia B, an X-linked genetic disorder which highly affects males, is a condition in which levels of Factor VIII are significantly decreased. Please describe the physiologic pathway which utilizes Factor VIII and describe the consequences of missing this factor from a physiologic perspective.what are the effects of PSTMB shown and why is it important to show effects of PSTMB in vitro effects of PSTMB on LDHA? https://www.nature.com/articles/s41598-019-40617-3
- Based on what is alfa-fetoprotein, explain what diseases of the fetus can be diagnosed with the alfa-fetoprotein test What kind of patient education can you give to a pregnant mother with a history of pre-eclampsia during her previous pregnancy?Fluorouracil is a structural analogue of thymine. The fluorine promotes enolization. How is this effect used in thetreatment of cancer?Heterozygotes for erythropoietic protoporphyria show only 20 to 30% residual ferrochelatase activity rather than the 50% that is normally expected for an autosomal dominant inherited disease. Provide a plausible explanation for this observation.
- 1. What are the tissue sources of Alkaline phosphatase? 2. What are Regan and Nagao isoenzymes? 3. State other approach of ALK determination through the existing isoenzymes. 4. Explain the role of L-tartrate in the determination of acid phosphatase . 5. Differentiate thymolphthalein monophosphate method from alpha naphthyl phosphate method of prostatic acid phosphate determination. 6. Why is acid phosphatase determination useful in establishing recent sexual intrusion as in the case of alleged rape?For vitamin supplement/ agouti mice and betel nut chewing/ cancer, describe the connection that they have with each otherWhat is the source of NH4+ in plant cells? Explain how NH4+ can be toxic to cells. How is this toxicity avoided?
