What is the reduction potential (DE) for the reaction catalyzed by isocitrate dehydrogenase if the citric acid cycle is fluxing? To get the answer scored correctly: Please report the answer to three decimal places. Example: 0.123 or -0.111 Do not include units.

What is the reduction potential (DE) for the reaction catalyzed by isocitrate dehydrogenase if the citric acid cycle is fluxing? To get the answer scored correctly: Please report the answer to three decimal places. Example: 0.123 or -0.111 Do not include units.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter23: Fatty Acid Catabolism

Section: Chapter Questions

Problem 21P: Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved...

See similar textbooks

Related questions

Q: How many ATP equivalents would be generated or used by the metabolism of 2 oxaloacetate to glucose?

A: Asked : ATP equivalents would be generated or used by the metabolism of 2 oxaloacetate to glucose

Q: Draw the Fischer projection of glucose and show its catabolism until it releases carbon dioxide via…

A: In order to track where every carbon of glucose went we use isotropic tracers experiments. Carbon of…

Q: Write a balanced equation for the complete metabolic oxidation of each of the following. Include Oz,…

A: One of the major catabolic pathways is beta oxidation where the molecules of fatty acid are broken…

Q: The enzyme Malate Dehydrogenase (MD) catalyzes the conversion of malate to oxaloacetate using…

A: Malate dehydrogenase (MDH) catalyzes the interconversion between malate and oxaloacetate which is a…

Q: In the citric acid cycle, the coenzyme NAD is required for which of the following reactions (Choose…

A: NAD or Nicotinamide adenine dinucleotide is a type of coenzyme that plays a crucial role in cellular…

Q: Which of the following cofactors is NOT used by the pyruvate dehydrogenase complex? a. NAD+ b. FAD…

A: The pyruvate formed by the process of glycolysis is converted into acetyl-CoA. The reaction is…

Q: Which one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be…

A: Pyruvate dehydrogenase complex is a group of non-covalently associated enzymes. It catalyzes…

Q: Using the symbols X-H2 and Y, draw a coupled oxidation-reduction reaction. Designate the molecule…

A: An increase in the rate of a reaction without changing itself and the final product, Catalyst is…

Q: The complete combustion of palmitate and glucose yields 9781 kJ ∙ mol−1 and 2850 kJ ∙ mol−1 of free…

A: Cellular Respiration is the oxidative process through which energy is obtained from the food. The…

Q: Certain tissues, such as the heart muscle, can use lactate as an energy substrate. How much ATP is…

A: Lactate generated by RBC is used by heart, it is oxidized to carbon di oxide and water, following…

Q: List four anabolic pathways that utilize citric acid cycle intermediates as starting material.

A: Introduction: The citric acid cycle is the most important metabolic pathway for the energy supply to…

Q: What is the significance of the ΔG°’ value of each step of Glycolysis? Why do some values classify…

A: The biochemical reactions energetics are best described in terms of the thermodynamic function…

Q: reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase

A: Oxidation reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase. Option A The two…

Q: . If palmitic acid is subjected to complete combustion in a bomb calorimeter, one can calculate a…

A: The oxidation of the palmitic acid produces 8 acetyl Co-A + 7FADH2 + 7NADH in 7 cycles of the…

Q: Explain what an oxidation–reduction reaction is and why the breakdown ofglucose in the presence of…

A: A chemical reaction is a process where two or more substances react together to form new or…

Q: Carbon dioxide loss, or decarboxylation, occurs in the Krebs Cycle with the transition of citrate to…

A: When there is energy demands in the cells, the acetyl CoA molecules produced through the oxidative…

Q: Consider the reaction: Malate + NAD +→ Oxaloacetate + NADH (AG° = +29.7 kJ/mol) A cell at 25°C has…

A: All cells require energy in the form of ATP to carry out a variety of functions, such as active…

Q: Classify each reaction or process as one that decreases or replenishes the pool of oxaloacetate…

A: Two molecules of pyruvate or pyruvic acid are formed by the aerobic breakdown of glucose by…

Q: The Km and kcat for fumarase with fumarate as a substrate are 5 × 10−6 M and 8 × 102 s−1,…

A: The citric acid cycle is the metabolic pathway, during which the oxaloacetate is formed from the…

Q: In the tricarboxylic acid cycle, L-malate is oxidized to oxaloacetate, using NAD+ as an oxidizing…

A: Given Values: Standard reduction potential for the conversion of oxaloacetate to malate = -0.166 V…

Q: What terms would best describe the above coupled reaction? (If the DGo for ATP hydrolysis into ADP +…

A: The Gibbs free energy change determines whether a biochemical reaction is favorable or not. It…

Q: Write balanced equations for each reaction in the citric acid cycle.

A: The citric acid cycle is a metabolic process that involves cellular respiration where oxidation of…

Q: Malonate is a competitive inhibitor of succinate dehydrogenase. What citric acid cycle…

A: Aerobic metabolism is a set of three basic metabolic processes that occur in cells to generate…

Q: Discuss the assertion that the Citric acid cycle is central for metabolism.

A: The citric acid cycle involves a series of chemical reactions to release stored energy through the…

Q: For the complete oxidation of 16 glucose molecules as a result of cellular respiration in plants,…

A: Respiration is defined as the breaking down of glucose into carbon dioxide, water and energy.

Q: What concentration of Proinebrium is required to achieve 50% inhibition of ethylene glycol…

A: Perineurium can be defined as a protective sheath present around the nerve fascicle and is made p of…

Q: Select the following enzymes that utlize a mechanism involving covalent catalysis. Select ALL that…

A: Covalent catalysis: The process of covalent catalysis involves the formation of covalent bonds…

Q: Which of the following statements are TRUE? Select an answer and submit. For keyboard navigation,…

A: Glucose is the simplest monosaccharide that is catabolized to generate ATP via respiration. Glucose…

Q: enzyme malate dehydrogenase catalyzes the conversion of malate to oxaloacetate in the final step…

A: In a reaction if a molecule is oxidized then other molecule must be reduced. This is called as…

Q: Why is it advantageous for citrate, the product of Reaction 1 of the citric acid cycle, to inhibit…

A: Glycolysis is the process by which one molecule of glucose is converted into two molecules of…

Q: Complete the following table by indicating the appropriate enzyme FULL names (from 1 to 4) affected…

A: The Krebs cycle (citric acid cycle) carry out the complete oxidation of acetyl CoA produced as the…

Q: in steps 3 and 5 of the citric acid cycle, the compounds are shortended by one carbon each time.…

A: The citric acid cycle is also known as the Krebs cycle. It is a series of chemical processes in the…

Q: If palmitic acid is subjected to complete combustion in a bomb calorimeter, one can calculate a…

A: The oxidation of the palmitic acid produces 8 acetyl Co-A + 7FADH2 + 7NADH in 7 cycles of the…

Q: If 1ªCO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase…

A: The citric acid (CAC) cycle is an aerobic metabolic pathway. During this pathway, the acetyl-CoA is…

Q: What is the net equation for the first 5 reactions of glycolysis?

A: Glycolysis is breakdown of glucose into pyruvate(aerobic oxidation) or lactate(anaerobic oxidation).…

Q: For the following reactions, name both the enzyme that catalyzes the reaction and the required…

A: The citric acid (CAC) cycle is the major metabolic pathway in the cell, which helps to form the…

Q: Write the equation for net citric acid cycle and calculate one cycle equivalent to how many ATP?

A: Aerobic cellular respiration takes place in the presence of oxygen. It has three major steps that…

Q: Which of the following statements are TRUE? Select an answer and submit. For keyboard navigation,…

A: Option (b) is incorrect because if the inhibitor will inhibit production of 1,3-bisphosphoglycerate…

Q: .What would happen in the Krebs cycle with the loss of activity of phosphoglycerate kinase? What…

A: Hi! Since you have posted multiple questions and have not mentioned which question to answer, we…

Q: The enzyme malate dehydrogenase catalyzes the conversion of malate to oxaloacetate in the final step…

A: The malate dehydrogenase enzyme catalyzes the conversion of malate to oxaloacetate in the TCA cycle.…

Q: What is the reduction potential (DE) for the reaction catalyzed by isocitrate dehydrogenase if the…

A: 0.152 is the reduction potential for the reaction catalyzed by isocitrate dehydrogenase if the…

Q: Write an equation for the pyruvate dehydrogenase reaction.

A: The pyruvate dehydrogenase (PDC) complex is considered as the crucial complex, which is known to…

Q: Select the following enzymes that utilize a mechanism where an enediol intermediate is formed. Check…

Q: Consider the malate dehydrogenase reaction from the citric acid cycle. Given the listed…

A: Malate dehydrogenase is citric acid cycle enzyme (metabolism) catalyzes the oxidation of malate into…

Q: Lactate can be converted into pyruvate by the enzyme lactate dehydrogenase and the coenzyme NAD+.…

A: Under normal, aerobic conditions, one molecule of glucose is converted to two molecules of pyruvate.…

Question

please help

What is the reduction potential (DE) for the reaction catalyzed by isocitrate
dehydrogenase if the citric acid cycle is fluxing?
To get the answer scored correctly: Please report the answer to three decimal
places. Example: 0.123 or -0.111
Do not include units.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step 3

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.

Similar questions

Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.
give five biological effects of disorders of the citric acid cycle
What step in the citric acid cycle in inhibited by fluorocitrate?
What are the two most common inhibitors of stepsof the citric acid cycle and the reaction catalyzed by pyruvatedehydrogenase?
The malaria parasite Plasmodium falciparum does not carry out oxidative phosphorylation and therefore does not use the citric acid cycle to generate reduced cofactors. Instead, the parasite converts amino acid–derived α ketoglutarate to succinate. Write an equation for the α-ketoglutarate → succinate conversion that follows (a) the oxidative (clockwise) path of the citric acid cycle or (b) the reductive (counterclockwise) path of the cycle.
The complete combustion of palmitate and glucose yields 9781 kJ ∙ mol−1 and 2850 kJ ∙ mol−1 of free energy, respectively. Compare these values to the free energy (as ATP) obtained though catabolism of palmitate and glucose under standard conditions. Which process is more efficient?
identify the reactions of the citric acid cycle that provide reducing power for the electron-transport chain a. conversion of succinyl-CoA to succinate b. conversion of fumarate to malate c. conversion of succinate to fumarate d. conversion of malate to oxaloacetate
Which reaction in the citric acid cycle is most analogous to the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate? What kind of enzymebound intermediate is formed in both reactions?
The ΔG°’ for the aldolase reaction of glycolysis in muscle is +22.8 kJ/mol. Why does the aldolase reaction proceed in the direction of glyceraldehyde-3-phosphate and dihydroxyacetone phosphate during glycolysis?
Given the following information, calculate the physiological ΔG of the isocitrate dehydrogenase reaction at 25°C and pH 7.0: [NAD+]/[NADH] = 8, [α-ketoglutarate] = 0.1 mM, and [isocitrate] = 0.02 mM. Assume standard conditions for CO2 (ΔG°′ is given in Table). Is this reaction a likely site for metabolic control?
Identify at least five biological effects of disorders of the citric acid cycle
What two major kinds of chemical reactions occur in the citric acid cycle, and how are these reactions indicated symbolically?