Which of the following best indicates a reason why Hisneeds to be a good proton donor (not acceptor) in the catalytic triad mechanism?So that it can create the alkoxide ion.So that it can create a hydroxyde ion.None of the other options is suitable because His's only role is to be a proton acceptor.So that the first product forms and leaves with the correct number of H's.So that it can stabilize the transition state.

Catalytic triad is a set of three coordinated amino acids that can be found in the active site of…

Answered: Which of the following best indicates a…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Which of the following best indicates a reason why Hisneeds to be a good proton donor (not acceptor) in the catalytic triad mechanism?

So that it can create the alkoxide ion.
So that it can create a hydroxyde ion.
None of the other options is suitable because His's only role is to be a proton acceptor.
So that the first product forms and leaves with the correct number of H's.
So that it can stabilize the transition state.

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