Answered: Which of the following is/are…

Science

Biology

Which of the following is/are characteristic(s) of dominant traits in pedigrees?

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 7CT: The following pedigree shows the pattern of inheritance of red-green color blindness in a family....

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Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?
Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?
You have been hired to produce a family tree for three generations of a family where a disorder called “blinky” syndrome is observed. People who suffer from blinky syndrome blink their eyes rapidly when they look at bright lights. In order to draw a pedigree chart for this family, you interview Mike and Annie. Neither suffer from this syndrome. Annie’s mother is normal, while Annie’s father blinked like crazy at bright lights. Annie has one sister and one brother and both of them are unaffected. While Annie’s sister has yet to have kids, her brother married a blinky sufferer. Mike’s mother is a blinker while his father is normal. Mike’s brother is just like their mother. In addition, this brother married a blinker. Mike’s sister is normal - as is her husband and their one boy. Draw a pedigree chart below in order to answer the following on the next page. Use the letters A and a for the genotypes. If more than one genotype is possible for an individual - you may write it as A with a…
You have been hired to produce a family tree for three generations of a family where a disorder called “blinky” syndrome is observed. People who suffer from blinky syndrome blink their eyes rapidly when they look at bright lights. In order to draw a pedigree chart for this family, you interview Mike and Annie. Neither suffer from this syndrome. Annie’s mother is normal, while Annie’s father blinked like crazy at bright lights. Annie has one sister and one brother and both of them are unaffected. While Annie’s sister has yet to have kids, her brother married a blinky sufferer. Mike’s mother is a blinker while his father is normal. Mike’s brother is just like their mother. In addition, this brother married a blinker. Mike’s sister is normal - as is her husband and their one boy. Draw a pedigree chart below in order to answer the following on the next page. Use the letters A and a for the genotypes. If more than one genotype is possible for an individual - you may write it as A with a…
In Figure 1-6, the students have 1 of 15 different heights,plus there are two height classes (4′11″ and 5′ 0″) forwhich there are no observed students. That is a total of17 height classes. If a single Mendelian gene can account for only two classes of a trait (such as purple orwhite flowers), how many Mendelian genes would beminimally required to explain the observation of 17height classes?
An individual with a form of red-green color blindness processes a genetically inherited trait that makes it difficult to distinguish red and green color hues. Red-green color blindness tends to skin generations and it is found much more often in men than in women. If a man who was normal and a woman who is a carrier for this form of colorblindness have a child, when the probability that the child will be red-green colorbind is: -0% -25% -50% -75% -100%
In man, there is gradation in eye color and resulting to 9 phenotypes. These are (in order of the number of additive alleles): light blue, medium blue, dark blue, gray, green, hazel, light brown, medium brown, dark brown. Mr. A (dark brown eyes) and Mrs. A’s (light blue eyes) daughter, marries a man whose genotype is the same as herself. What is the probability that they could have: Dark brown eyed child? Hazel-eyed? What eye color is most likely to occur and what is its probability?
Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites are heterozygotes. Genetic testing can diagnose heterozygotes. Should a genetic screening program for cystic fibrosis be instituted? Should the federal government fund it? Should the program be voluntary or mandatory, and why?
The young woman shown at right has albinismvery pale skin, white hair, and pale blue eyes. This phenotype is due to the absence of melanin, which imparts color to the skin, hair, and eyes. It typically is caused by a recessive allele. In the following situations, what are the probable genotypes of the father, the mother, and their children? a. Both parents have normal phenotypes; some of their children are albino and others are not. b. Both parents and all their children are albino. c. The mother is not albino, the father is albino, and one of their four children is albino.
A proband female with an unidentified disease seeks the advice of a genetic counselor before starting a family. Based on the following data, the counselor constructs a pedigree encompassing three generations: (1) The maternal grandfather of the proband has the disease. (2) The mother of the proband is unaffected and is the youngest of five children, the three oldest being male. (3) The proband has an affected older sister, but the youngest siblings are unaffected twins (boy and girl). (4) All the individuals who have the disease have been revealed. Duplicate the counselors feat
Sunflowers with flowers 10 cm in diameter are crossed with a plant that has 20-cm flowers. The F1 plants have flowers 15 cm in diameter. In the F2 generation, 4 flowers are 10 cm in diameter and 4 are 20 cm in diameter. Between these are 5 phenotypic classes with diameters intermediate to those at the extremes. a. Assuming that the alleles that contribute to flower diameter act additively, how many genes control flower size in this strain of sunflowers? b. How much does each additive allele contribute to flower diameter? c. What size flower makes up the largest phenotypic class?
Pedigree Analysis Is a Basic Method in Human Genetics Pedigree analysis permits all of the following except: a. an orderly presentation of family information b. the determination of whether a trait is genetic c. the determination of whether a trait is dominant or recessive d. an understanding of which gene is involved in a heritable disorder e. the determination of whether a trait is sex-linked or autosomal