Your friend need to purify a sample left behind by an older graduate student to isolate the aminonapthalene derivative A. Knowing the content of the sample, your friend suggested a rapid liquid-liquid extraction to purify up the sample. NH2 OH B C 1M NaOH ELOAC Aqueous Organic NH |NAHCO3 ELOAC Aqueous Organic NH2 Final organic phase Your chemical intuition tells you this plan is wrong. a) Why? What is wrong with the steps proposed in the flow chart? What would your friend isolate in the final organic phase (the solution represented by a rectangle) if she were to execute her plan as described?

Your friend need to purify a sample left behind by an older graduate student to isolate the aminonapthalene derivative A. Knowing the content of the sample, your friend suggested a rapid liquid-liquid extraction to purify up the sample. NH2 OH B C 1M NaOH ELOAC Aqueous Organic NH |NAHCO3 ELOAC Aqueous Organic NH2 Final organic phase Your chemical intuition tells you this plan is wrong. a) Why? What is wrong with the steps proposed in the flow chart? What would your friend isolate in the final organic phase (the solution represented by a rectangle) if she were to execute her plan as described?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

1. Explain the concept of Azeotropic distillation for the separation of Acetone, chloroform with neat sketch. (4 + 1 = 5Marks) . 2. Explain the application of extractive distillation in nitric acid dehydration using suitable solvent with neat sketch . (4 + 1 = 5Marks) .
In UV spectroscopy we are taught the effects of polarity on liquid chemistries that may undergo bathochromic red shif, hypochromic blue shift , hypsochromic decrease in absorbance and aborptivity and hyperchromic effects a increase in absorbance or absorptivity. The cause for hyperchromic shifts has one explanation that appears to make sence and that is related to Auxochromic groups or the effect on the chromophore for for a new chromophore with the auxo group that causes both a hyperchromic and bathochromic red shift. Question 1: Does this dual shift in absorbance and wavelength occur in non-liquid sustances like plastics e.g. polypropylene, polyethylene, condensation polymers like PET and Polycarbonate? Question 2: Is there a way to predict level of hyperchromic shift based on the auxochromic group or do we need to know the chromophore? Question 3: Are there known examples of chromophore and Auxochromic groups that provide various molar extinction or absorptivity or absorbance…
Q1: Give one lysis buffer that is commonly used for western blotting experiments and include its components Q3: To make sure that you used a similar amount of samples, what important step should be done before proceeding the electrophoresis stage? Q4. Why is it necessary to store the prepared lysates in a very low temperature?
Mass of maleic anhydride used: 5.1296 gram Volume of furan used: 3.25 ml Volume of THF used: approx. 16ml The reaction mixture was allowed to stand undisturbed for one week, whereupon, gem-like, colorless to white, prismatic crystals were isolated from the solvent matrix and allowed to air dry. When dry, the mass of the crystals was determined to be: 4.6732 gram. One small crystal was selected and ground to a fine powder for melting point measurement. The powder was observed to melt at 117 – 118 deg C. About 1ml of a saturated solution of product dissolved in DMSO-d6 was prepared and placed in an NMR tube. Subsequently, proton, carbon-13 and DEPT NMR spectra were acquired. Analysis Write the reaction using structural formulas. Calculate percent yield (show work) What does the measured melting point suggest?
A newly synthesized drug was found to have a carboxyl group, an imide and a sulfonamide group. The first type of method to consider in this drug molecule’s quantitatve analysis is: a. Non-aqueous Alkalimetryb. Non-aqueous Acidimetryc. Aqueous Alklaimetryd. Aqueous Acidimetry
It has been noticed that adulteration of palm oil with carcinogenic dyes are on the rise. Use your knowledge in analytical processes to systematically process adultrated palm oil to gain qualitative and quantitative information spectroscopically about any added toxic.Explain also the basis for your protocol of choice
Any special precautions or purifications of the reagents required? Limiting and excess reagent? Why is excess necessary? 4,4'-DIBROMOBIPHENYL [Biphenyl, 4,4'-dibromo-] Submitted by Robert E. Buckles and Norris G. Wheeler1. Checked by R. S. Schreiber, Wm. Bradley Reid, Jr., and Robert W. Jackson. 1. Procedure In a 15-cm. evaporating dish is placed 15.4 g. (0.10 mole) of finely powdered biphenyl (Note 1). The dish is set on a porcelain rack in a 30-cm. desiccator with a 10-cm. evaporating dish under the rack containing 39 g. (12 ml., 0.24 mole) of bromine. The desiccator is closed, but a very small opening is provided for the escape of hydrogen bromide (Note 2). The biphenyl is left in contact with the bromine vapor for 8 hours (or overnight). The orange solid is then removed from the desiccator and allowed to stand in the air under a hood for at least 4 hours (Note 3). At this point, the product weighs about 30 g. and has a melting point in the neighborhood of 152°. The crude…
Provide details about the reaction workup. 4,4'-DIBROMOBIPHENYL [Biphenyl, 4,4'-dibromo-] Submitted by Robert E. Buckles and Norris G. Wheeler1. Checked by R. S. Schreiber, Wm. Bradley Reid, Jr., and Robert W. Jackson. 1. Procedure In a 15-cm. evaporating dish is placed 15.4 g. (0.10 mole) of finely powdered biphenyl (Note 1). The dish is set on a porcelain rack in a 30-cm. desiccator with a 10-cm. evaporating dish under the rack containing 39 g. (12 ml., 0.24 mole) of bromine. The desiccator is closed, but a very small opening is provided for the escape of hydrogen bromide (Note 2). The biphenyl is left in contact with the bromine vapor for 8 hours (or overnight). The orange solid is then removed from the desiccator and allowed to stand in the air under a hood for at least 4 hours (Note 3). At this point, the product weighs about 30 g. and has a melting point in the neighborhood of 152°. The crude 4,4'-dibromobiphenyl is dissolved in 75 ml. of benzene, filtered, and cooled to 15°.…
You are working in a plant biology laboratory that analyzes plant hormones. Your supervisor wants to use your organic chemistry knowledge to develop a protocol to separate kinetin from jasmonic acid in plant extracts. Using the same extraction conditions as for Experiment 2 (i.e. using dichloromethane and Na2CO3 aqueous solution), devise a procedure to isolate jasmonic acid. You can present your procedure in point form or as a flow chart. You can use standard reagents and techniques previously used in CHEM 266L, and state in which layer of the extraction each compound is found through your procedure.
Why is it important to thoroughly vortex the contents of the vial after adding reagent 4 (Steps 3 and 4., stage 1). To ensure that the two immiscible solvents come into contact with each other, permitting the derivatization reactions to occur. B.To ensure that the solution is mixed thoroughly. To ensure that all the amino acids are transferred to the lower aqueous layer so that a full extraction occurs. To remove all the interferring compounds by transferring them to the upper organic layer Hint: Reagent 4 is the derivatizing agent dissolved in octane.
please don't provide handwrittin solution... Synthesis
What solvent below would be able to be used in a liquid-liquid extraction where hexane (CH3CH2CH2CH2CH2CH3) was used as the organic solvent?