Zinc finger nuclease is a Gene editing tool: which uses a site-specific endonucleases containing a DNA-cleavage domain and a modular DNA-binding domain RNA-guided endonucleases programmable nucleases Exonuclease
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
1. Zinc finger nuclease is a Gene editing tool:
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which uses a site-specific endonucleases containing a DNA-cleavage domain and a modular DNA-binding domain |
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RNA-guided endonucleases |
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programmable nucleases |
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Exonuclease |
2.
Lipoplexes trapped in endosomes prevent destruction by lysosomes due to
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the inclusion within the liposomes of electrically neutral lipids |
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inclusion within the liposomes of electrically charged lipids |
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Lysosomes do not recognize them as foreign |
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pH |
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