MICROBIOLOGY:PRINCIPLES+..(LL)-W/ACCESS
9th Edition
ISBN: 9781119029212
Author: Black
Publisher: WILEY
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Chapter 1, Problem 5CTQ
The completion of chromosomal mapping and sequencing of genes in the Human Genome Project has been one of humanity’s greatest accomplishments, yet it really serves as just the beginning for a new era of genomic science.
- (a) Can you think of new burgeoning fields of science that will result from the newly acquired sequencing data?
- (b) Antibiotics are effective because of their selective killing of bacterial and not animal cells. Can you think of ways in which comparing bacterial genomes to the human genome might result in additional cures of bacterial infections/diseases?
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In 1995, Hamilton Smith, Craig Venter and co-workers published the first complete genome sequence of a self-sustaining organism, that of the bacterium Haemophilus influenzae. Analysis of the genome sequence revealed that the organism does not have a gene that could encode a telomerase enzyme. What is the potential evolutionary consequence of this? Explain your answer.
Describe the three basic goals of the Human Genome Project. What are at least three things we have learned from the project? Do you believe it was a worthwhile project? Why or why not?
Human Genome ProjectIn 2003, the Human Genome Project was successfully completed, determining the exact sequence of the entire human genome, which is made up of 3 billion nucleotide base pairs. The data generated from the Human Genome Project is freely available online to anyone. Many researches and innovations stemmed from the HGP, allowing the identifications of 1 800 disease genes. Many of the corporations using the results from the HGP are privately funded, and research is being done for profit even though the HGP results are provided freely.Identify one advantage and one disadvantage of corporate funding and patenting genetic research results.
Chapter 1 Solutions
MICROBIOLOGY:PRINCIPLES+..(LL)-W/ACCESS
Ch. 1 - List three reasons to study microbiology.Ch. 1 - What is the difference between microbiology and...Ch. 1 - Prob. 1.3SCCh. 1 - List five bacterial diseases and five viral...Ch. 1 - Prob. 2.1SCCh. 1 - State the germ theory of disease. Try to think of...Ch. 1 - How did Pasteurs experiment with swan-necked...Ch. 1 - Why was the French microbiologists method of broth...Ch. 1 - What were the scientific contributions of Jenner,...Ch. 1 - Prob. 3.2SC
Ch. 1 - What is the Human Genome Project? How has...Ch. 1 - Prob. 1CCSCh. 1 - Prob. 1CTQCh. 1 - Can you think of some reasons why it might be hard...Ch. 1 - As often happens in science, one observation or...Ch. 1 - It is likely that others beside Anton van...Ch. 1 - The completion of chromosomal mapping and...Ch. 1 - Prob. 6CTQCh. 1 - Prob. 1SQCh. 1 - Conclusive evidence of thriving microbial life has...Ch. 1 - Which of the following is not true? (a) A single...Ch. 1 - Which is false regarding Archaea? (a) They lack a...Ch. 1 - Why are microbes important to study and how are...Ch. 1 - Prob. 6SQCh. 1 - Prob. 7SQCh. 1 - Animals such as worms and ticks are too large to...Ch. 1 - Prob. 9SQCh. 1 - Prob. 10SQCh. 1 - What triggered the development and establishment...Ch. 1 - Prob. 12SQCh. 1 - Prob. 13SQCh. 1 - The biggest obstacle in the acceptance and...Ch. 1 - Match the following terms to the appropriate...Ch. 1 - Prob. 16SQCh. 1 - Prob. 17SQCh. 1 - Prob. 18SQCh. 1 - Describe the contributions of the following...Ch. 1 - Prob. 20SQCh. 1 - Prob. 21SQCh. 1 - Prob. 22SQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- describe some of the key findings from the Human Genome Project so that you can picture in a general fashion how these 3 billion nucleotides are organized.arrow_forwardWhat are the overall benefits/consequences of the Human Genome Project and the ability to quickly perform DNA sequencing?arrow_forwardIn 1994, telomerase activity was discovered in human cancer cell lines. Although telomerase is not active in human somatic tissue, human somatic cells do contain the genes for telomerase proteins and telomerase RNA. Since inappropriate activation of telomerase may contribute to cancer, why do you think the genes coding for this enzyme have been maintained in the human genome throughout evolution? Are there any types of human body cells where telomerase activation would be advantageous or even necessary? Explain.arrow_forward
- What is the purpose of the Human Genome Project? Why do researchers want to know the details of the human genome?arrow_forwardA researcher sequences the genome of a variety of bacterial and eukaryotic cells. She finds that the bacterial genome is smaller, but that there are more genes for a given number of base pairs in the eukaryotic cells. In other words, there are fewer genes per unit of length of DNA in the eukaryotic cells. What do you predict she will find if she examines the DNA more closely? A. All of the bacterial DNA consists of coding sequences, but this is not true of the eukaryotic DNA. B. There are more repetitive sequences in the eukaryotic DNA than in the bacterial DNA. C. There are densely packed genes in the eukaryotic DNA that were not immediately distinguishable during the first analysis. D. The bacteria have larger quantities of noncoding DNA than the eukaryotic cells.arrow_forwardHuman Genome ProjectIn 2003, the Human Genome Project was successfully completed, determining the exact sequence of the entire human genome, which is made up of 3 billion nucleotide base pairs. The data generated from the Human Genome Project is freely available online to anyone. Many pieces of research and innovations stemmed from the HGP, allowing the identifications of 1 800 disease genes. Many of the corporations using the results from the HGP are privately funded, and research is being done for profit even though the HGP results are provided freely. Identify one advantage and one disadvantage of corporate funding and patenting genetic research results.arrow_forward
- Humans have engaged in genetic manipulation for millennia, producing plant and animal varieties through selective breeding and hybridization that significantly modify genomes of organisms. Why do you think modern genetic engineering, which often entails introducing or modifying only one or a few genes, has met with so much opposition? Should some forms of genetic engineering be of greater concern than others? Explain.arrow_forwardA molecular biologist wants to isolate a gene from a scorpion that encodes the deadly toxin found in its stinger, with the ultimate purpose of transferring this gene to bacteria and producing the toxin for use as a commercial pesticide. Isolating the gene requires a DNA library. Should the molecular biologist create a genomic library or a cDNA library? Explain your reasoning.arrow_forwardPlease use information from the text below and your knowledge of biology to answer the final two (2) questions. In 2003, as a result of the Human Genome Project, the complete sequence of all the bases in human DNA was released to the public. Although knowing the entire sequence of bases has proven valuable, scientists are currently working to map genes. Mapping genes involves determining the exact location of each gene. Since much of human DNA does not code for a protein, it is challenging to figure out which segments are actual genes. Often, scientists look at the percent composition of bases in a segment of DNA. If the segment of DNA has a large percentage of C and G bases (together over 50%), it is likely that it is a gene and codes for a protein. 10. Is it likely this segment of DNA codes for a protein? State 'yes' or 'no' AND support your answer using information from the text.arrow_forward
- Please use information from the text below and your knowledge of biology to answer the final two (2) questions. In 2003, as a result of the Human Genome Project, the complete sequence of all the bases in human DNA was released to the public. Although knowing the entire sequence of bases has proven valuable, scientists are currently working to map genes. Mapping genes involves determining the exact location of each gene. Since much of human DNA does not code for a protein, it is challenging to figure out which segments are actual genes. Often, scientists look at the percent composition of bases in a segment of DNA. If the segment of DNA has a large percentage of C and G bases (together over 50%), it is likely that it is a gene and codes for a protein. 9. A scientist analyzed the bases in a segment of DNA from a human skin cell to determine if it codes for a protein. The base A (Adenine) is 11% of the bases in this segment of DNA. Calculate the percentage of bases that would be C…arrow_forwardThe genome of what free living organism was first fully sequenced, and when?arrow_forwardHow many Illumina clusters would you need to generate 15X coverage of the human genome, assuming your read lenght is 600 bp? (assume a human genome size of 3 billion bp) - 2.5 billion - 75 million - 7 million - 100 millionarrow_forward
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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License