Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Textbook Question
Chapter 10, Problem 15P
A normal chromosome and its homolog carrying a paracentric inversion are given. The dot (•) represents the centromere.
Normal ABC •DEFGHIJK
Inversion abc •djihgfek
Diagram the alignment of chromosomes during prophase I.
Assume a crossover takes place in the region between F and G. Identify the gametes that are formedfollowing this crossover, and indicate which gametes are viable.
Assume a crossover takes place in the region between A and B. Identify the gametes that are formed by this crossover event, and indicate which gametes are viable.
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A normal chromosome A B C D * E F G H I J K has mutated toA B C F E * D G H I J K J K.This is an example of a _________________ chromosomal mutation. ( * denotes the centromere)
Group of answer choices
Pericentric inversion of DEF and tandem duplication of JK.
Pericentric inversion of DEF and displaced duplication of JK
Paracentic inversion of DEF and displaced duplication of JK.
Paracentric inversion of DEF and tandem duplication of JK.
Consider the following "pericentric" ("around the center") inversion. In one an individual, a simplified 8-gene sequence along one chromosome is 1234
5678 while a pericentric inversion occurred on their other homologous
chromosome, resulting in the sequence 1265 4378 (the dot represents the centromere). Draw these homologous chromosomes lined up (as during crossing over, in Prophase l). If a crossover event occurred between gene locus 3 and 4 (slicing between them) on the original chromosome, what would the crossover products look like? What would be the "problem" with each of the chromosomes that result?
An initial crossover event will occur between A and B, as indicated in the corresponding image. After this initial event occurs, a second cross over event occurs (not illustrated) involving the products of the first crossover event. Given the chromosome organization below, which two chromatids of the bivalent were involved and between which genes did the second crossover event occur to produce the indicated chromosomes?
a. A B c, A b c, a B C, and a b C
b. A B C, A B C, a b c, and a b c (return to the original crossover depicted in the image, and then determine how the second crossover event produced this arrangement
Chapter 10 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 10 - 10.1 Give descriptions for the following...Ch. 10 - 10.2 The human genome contains contains base...Ch. 10 - In eukaryotic DNA, Where are you most likely to...Ch. 10 - 10.4 Describe the importance of light and dark G...Ch. 10 - Human late prophase karyotypes have about 2000...Ch. 10 - Prob. 6PCh. 10 - From the following list, identify the types...Ch. 10 - 10.8 If the haploid number for a plant species is...Ch. 10 - Mating between a male donkey (2n=64) and a female...Ch. 10 - A researcher interested in studying a human gene...
Ch. 10 - 10.11 In what way does position effect variegation...Ch. 10 - 10.12 A pair of homologous chromosomes in...Ch. 10 - 10.13 An animal heterozygous for a reciprocal...Ch. 10 - Dr. Ara B. Dopsis has an idea he thinks will be a...Ch. 10 - A normal chromosome and its homolog carrying a...Ch. 10 - The accompanying chromosome diagram represents a...Ch. 10 - 10.17 Histone protein isolated from pea plants...Ch. 10 - 10.18 A survey of organisms living deep in the...Ch. 10 - In humans that XX/XO mosaics, the phenotype is...Ch. 10 - 10.20 A plant breeder would like to develop the...Ch. 10 - In Drosophilia, seven partial deletion (1to7)...Ch. 10 - Two experimental varieties of strawberry are...Ch. 10 - 10.23 In the tomato, Solanum esculentum, tall ()...Ch. 10 - A boy with Down syndrome (trisomy 21) has 46...Ch. 10 - Experimental evidence demonstrates that the...Ch. 10 - Prob. 26PCh. 10 - Genomic DNA from the nematode worm...Ch. 10 - 10.28 A small population of deer living on an...Ch. 10 - A eukaryote with a diploid number of 2n=6 carries...Ch. 10 - Prob. 30PCh. 10 - For the following crosses, determine as accurately...Ch. 10 - A healthy couple with a history of three previous...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Rice has a chromosome number of 2n = 24. If different euploids and anaeuploids are available in rice, identifythe chromosomal mutation, chromosome configuration, chromosome number, and/or type of gametes in each of the mutations below. Complete the table. Example: for 10B, the answer is "10 II + 2 I"arrow_forwardWhich type(s) of chromosomal aberrations result from chromosomal breaks on different chromosomes? Assume that a heterozygote for the aberration is viable. Select all correct answers. A.)Robertsonian translocation B.)reciprocal translocation C.)tandem duplication D.)paracentric inversion E.)pericentric inversion F.)large deletionarrow_forwardA crossover has occurred in the bivalent shown figure.If a second crossover occurs in the same region between these twogenes, which two chromatids would be involved to produce thefollowing outcomes?A. 100% recombinantsB. 0% recombinantsC. 50% recombinantsarrow_forward
- A chromosome of genotype C D recombines with a homolog of genotype c d during meiosis when Spo11 produces a double-strand break between genes C and D. If anticrossover helicase disentangles the invading strand, the likely outcome would be A) two C D and two c d gametes. B) two C d and two c D gametes. C) one C D, one C d, one c D, and one c d gamete. D) four C D gametes. E) four c d gametesarrow_forwarda) Are the genes linked? Please explain SPECIFICALLY how you can distinguish between linked and unlinked genes in this instance. b) If the two genes are linked, calculate the % recombination between ser and thr. Show the formula used, as well as all of your calculations. c) Draw a single map illustrating the arrangement of the two genes on the chromosome with respect to each other and to the centromere of the chromosome. Make sure to map ALL three distances.arrow_forwardConsider the following two wild type chromosomes: AB•CDEFGH I•JKLMN What kind of rearrangement is observed in the mutated chromosomes below? AB•CDEKLMNFGH I•J A. reciprocal translocation B. non-reciprocal translocation C. displaced duplication D. pericentric inversion E. paracentric inversionarrow_forward
- why The chromatids formedby recombination within the inversion loop of a paracentric inversionheterozygote are genetically unbalanced ?arrow_forwardConsider Cyclic Crossover on two Parent chromosomes: Parent1 = A0846172593B and Parent2 = 394B5721608A . Assume that Parent2 is the default and that crossover will occur at the data value in the 1st position. What will the child chromosome be?arrow_forwardwhy The chromatids formedby recombination within the inversion loop of a paracentric inversionheterozygote containtwo centromeres or none, instead of the normal one ?arrow_forward
- For each of the terms in the left column, choose thebest matching phrase in the right column.a. reciprocal translocation 1. lacking one or morechromosomes or having oneor more extra chromosomesb. gynandromorph 2. movement of short DNAelementsc. pericentric 3. having more than two completesets of chromosomesd. paracentric 4. exact exchange of parts of twononhomologous chromosomese. euploids 5. excluding the centromeref. polyploidy 6. including the centromereg. transposition 7. having complete sets ofchromosomesh. aneuploids 8. mosaic combination of maleand female tissuearrow_forwardWith detailed accounts of their various forms, explain any three of the following chromosomal aberrations: a) Deletions b) Duplications c) Translocations d)Inversionarrow_forwardA pair of paralogous repeats, A and B, have 96% sequence similarity and therefore can promote non-allelic homologous recombination (NAHR). They exist in four possible arrangements in a genome, illustrated below as arrangements 1 – 4. What is the result of NAHR between repeats A and B in arrangement 1? A.Translocation between chromosomes 1 and 2 resulting in monocentric chromosomes B.Deletion or duplication of the region between A and B C.Translocation between chromosomes 1 and 2 resulting in acentric and dicentric chromosomes D.Inversion of the region between A and Barrow_forward
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