To tell:
Why physicians do not invariably prescribe the antimicrobial with the largest zone of inhibition.
Introduction:
The disk-diffusion test is a method applied to evaluate the antibiotic susceptibility. In petri plate (where an antibiotic disk is placed on a uniformly inoculated test pathogen), the clear area (measured in diameter) showing the absence of bacterial growth is referred to as the zone of inhibition. The minimal inhibitory concentration (MIC) is the least antibiotic concentration required to inhibit visible growth of bacteria. The minimal bactericidal concentration (MBC) is the lowest concentration of antibiotic required to kill the bacteria. But, it cannot be used to determine whether an antibiotic is bactericidal or just bacteriostatic. In order to determine MIC and MBC of an antibacterial drug, a broth dilution test is useful.
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Chapter 10 Solutions
Microbiology: With Diseases By.. -Modern Access
- If your hospital laboratory isolates streptococcus pneumoniae from four patients on the same day, would you have to test the antimicrobial susceptibility of each isolate? Why or why not?arrow_forwardWhat would your plate look like if we did not use aseptic technique to place the antimicrobial disks on the plate and what would happen if we decreased or increased the concentration of antimicrobials used on the plates?arrow_forwardWhy is it necessary to develop new generations of antimicrobial medications?arrow_forward
- What would our plate look like if no aseptic techniques were used to place the antimicrobial disks on the platearrow_forwardGiven that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?arrow_forwardWhat are the major actions of antimicrobial agents? What criteria are used in the selection of antimicrobial agents?arrow_forward
