Biochemistry: Concepts and Connections
1st Edition
ISBN: 9780321839923
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Textbook Question
Chapter 10, Problem 5P
In the following situations, what is the free energy change if 1 mole of
a. In the absence of a membrane potential.
b. When the transport is opposed by a membrane potential of 70 mV.
c. In each case, will hydrolysis of 1 mole of ATP suffice to drive the transport of 1 mole of ion, assuming pH 7.4 and the following cytoplasmic concentrations: ATP =4.60 mM, Pi = 5.10 mM, ADP = 310
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You are considering transport of Fe3+ out of a biological cell with a membrane potential of -60 mV. What is the value for delta psi in this case? (Make sure you express this value in proper units, i.e., as you would enter this value into the change in free energy of transport equation.)
In the following situations, what is the free energy change if 1 mole of Na+is transported across a membrane from a region where the concentration is1 μM to a region where it is 100 mM?(Assume T = 37 °C.) (a) In the absence of a membrane potential. (b) When the transport is opposed by a membrane potential of 70 mV. (c) In each case, will hydrolysis of 1 mole of ATP suffice to drive the transport of 1 mole of ion, assuming pH 7.4 and the following cytoplasmic concentrations: ATP = 4.60 mM, Pi = 5.10 mM, ADP = 310 μM?
In the situations described below, what is the free energy change if 1 mole of Na+ is transported across a membrane from a region where the concentration is 48 μM to a region where it is 110 mM? (Assume T=37∘C.) When the transport is opposed by a membrane potential of 70 mV.
Chapter 10 Solutions
Biochemistry: Concepts and Connections
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- In the situations described below, what is the free energy change if 1 mole of Na* is transported across a membrane from a region where the concentra- tion is 1 µM to a region where it is 100 mM? (Assume T = 37 °C.) (a) In the absence of a membrane potential. (b) When the transport is opposed by a membrane potential of 70 mV. (c) In cach case, will hydrolysis of 1 mole of ATP suffice to drive the trans- port of 1 mole of ion, assuming pH 7.4 and the following cytoplamic concentrations: ATP= 4.60 mM, P = 5.10 mM, ADP = 310 µM?arrow_forwardIn the situations described below, what is the free energy change if 1 mole of Na+ is transported across a membrane from a region where the concentration is 48 μM to a region where it is 110 mM? (Assume T=37∘C.) In the absence of a membrane potential.arrow_forwardSuppose that the concentration of CI outside the cell is 100 and inside the cell is 10 mmol/liter. The Nernst equation at 20°C is: Eton = 58 millivolts/z- [10810 (m)] [lonlin You set the membrane voltage at 0 millivolts using a voltage clamp, and measure membrane current. If Cl is the only ion crossing the membrane, you would expect to see: Onegative charges flowing into the cell negative charges flow out of the cell 0 current the membrane hyperpolarizes (becomes more negative)arrow_forward
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