EBK FUNDAMENTALS OF BIOSTATISTICS
8th Edition
ISBN: 9780101123402
Author: Rosner
Publisher: YUZU
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 10, Problem 8P
Gastroenterology
Two drugs (A, B) are compared for the medical treatment of duodenal ulcer. For this purpose, patients are carefully matched with regard to age, gender, and clinical condition. The treatment results based on 200 matched pairs show that for 89 matched pairs both treatments are effective; for 90 matched pairs both treatments are ineffective; for 5 matched pairs drug A is effective, whereas drug B is ineffective; and for 16 matched pairs drug B is effective, whereas drug A is ineffective.
What test procedure can be used to assess the results?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Which test do I need to run ?
A phamaceutical company wants to test the effectiveness of a new allergy drug. The company identifies 250 females 30-35 years old who suffer from severe allergies.
The subjects are randomly assigned into two groups. One group is given the new allergy drug and the other is given a placebo that looks exactly like the new allergy
drug. After six months, the subjects' symptoms are studied and compared. Answer parts (a) through (c) below.
O B. The experimental units are the symptoms from the drug. The treatment is the new allergy drug.
O C. The experimental unit is the new allergy drug. The treatments are the severe allergies the patients suffer from.
O D. The experimental units are the 30- to 35-year-old females being given the treatment. The treatment is the new allergy drug.
(b) Identify a potential problem with the experiment design being used and suggest a way to improve it. Choose the correct answer below.
O A. There may be a bias on the part of the patients since they do not know if…
Suppose you were presented with the results of a study comparing two different training methods for basketball athletes. You are told 32 athletes were randomly assigned to the two groups so that 16 were in the group A and 16 were in the group B. At the end of the session, the average scores (wins versus losses) of the two groups/teams were compared and a difference of 10% was observed ( the first team had 10% more wins than the second). The coach observer reports two- sample t-test shows this difference is statistically significant. How would you interpret these findings? What questions or concerns would you have? How might this type of study be improved?
Hint: Consider the possibility that the test performed was not the appropriate one.
Chapter 10 Solutions
EBK FUNDAMENTALS OF BIOSTATISTICS
Ch. 10.2 - What is a contingency table?Ch. 10 - Consider the Physicians Health Study data...Ch. 10 - Consider the Physicians Health Study data...Ch. 10 - Answer Problem 10.1 if a one-sided test with power...Ch. 10 - Consider the Physicians Health Study data...Ch. 10 - Answer Problem 10.4 if compliance is as given in...Ch. 10 - Consider the Physicians Health Study data...Ch. 10 - Consider the Physicians Health Study data...Ch. 10 - Gastroenterology Two drugs (A, B) are compared for...Ch. 10 - Gastroenterology Two drugs (A, B) are compared for...
Ch. 10 - Gastroenterology Two drugs (A, B) are compared for...Ch. 10 - Sexually Transmitted Disease Suppose researchers...Ch. 10 - Cancer A 1980 study investigated the relationship...Ch. 10 - Ophthalmology Retinitis pigmentosa is a disease...Ch. 10 - Pulmonary Disease One important aspect of medical...Ch. 10 - Prob. 24PCh. 10 - Hepatic Disease Refer to Data Set HORMONE.DAT, at...Ch. 10 - Health Services Administration In the Harvard...Ch. 10 - Health Services Administration In the Harvard...Ch. 10 - Orthopedics A study was performed among subjects...Ch. 10 - Prob. 54PCh. 10 - Prob. 55PCh. 10 - Prob. 56PCh. 10 - Prob. 57PCh. 10 - Prob. 58PCh. 10 - Cancer A topic of current interest is whether...Ch. 10 - Cancer A topic of current interest is whether...Ch. 10 - Ophthalmology A 5-year study among 601...Ch. 10 - Prob. 74PCh. 10 - Prob. 77PCh. 10 - Prob. 87P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, statistics and related others by exploring similar questions and additional content below.Similar questions
- What is meant by the sample space of an experiment?arrow_forwardWhat is an experiment?arrow_forwardA company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance without blocking to test whether there is evidence of a significant difference in mean sales of different package designs. Use alpha = 0.01. What are the mean squares for error? Please provide your answer to the nearest two decimal places.arrow_forward
- A company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 O 0.0642 and 0.0435 2 0.0642 and 0.0038 O 0,0435 and 0.0028 0.0038 and 0.0028 45 0.0028 and 0.0038 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 Enter the above data into a suitable software and then conduct an analysis of variance with blocking (analyze this data as a complete block design) to test further whether there is evidence of a significant difference in mean sales of different package designs. Use alpha=0.01. 49 What are p-values to determine whether all…arrow_forwardA company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance without blocking to test whether there is evidence of a significant difference in mean sales of different package designs. Use alpha=0.01. What is the conclusion for the null hypothesis that all treatment means are equal? O Do not reject HO. There is sufficient evidence to conclude that the average sales for all stores are not…arrow_forwardA company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance with blocking (analyze this data as a complete block design) to test further whether there is evidence of a significant difference in mean sales of different package designs. Use alpha=0.01. What are the sums of squares for Blocks? Provide your answer to the nearest 2 decimal places.arrow_forward
- A company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance without blocking to test whether there is evidence of a significant difference in mean sales of different package designs. Use alpha = 0.01. the p-value associated with the observed test statistic? Please provide your answer to the nearest fou decimal places.arrow_forwardA company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance with blocking (analyze this data as a complete block design) to test further whether there is evidence of a significant difference in mean sales of different package designs. Use alpha = 0.01. What are the degrees of freedom for error?arrow_forwardA company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance without blocking to test whether there is evidence of a significant difference in me sales different packa designs. Use alpha = 0.01. What are the sums of squares for treatments? Please provide your answer to the nearest two decimal places.arrow_forward
- A company wishes to evaluate the effect of package design on one of its products, a certain brand of cereal. The four package designs are to be tested in different stores throughout a large city. There are 20 stores available for the study. The amount of cereal sold is known to vary depending on the size of the stores. The 20 stores are divided into five groups of four stores each by size. The following sales figures ($1000s) were obtained after a 1-month period. Stores Design A Design B Design C Design D 1 40 33 37 38 2 45 27 32 40 3 43 31 30 41 4 44 38 40 42 5 56 45 49 42 Enter the above data into a suitable software and then conduct an analysis of variance with blocking (analyze this data as a complete block design) to test further whether there is evidence of a significant difference in mean sales of different package designs. Use alpha = 0.01. What are the mean squares for Treatments? Provide your answer to the nearest 2 decimal places.arrow_forwardA new over-the-counter medicine to treat a sore throat is to be tested for effectiveness. The makers of the medicine take two random samples of 25 individuals showing symptoms of a sore throat. Group 1 receives the new medicine and Group 2 receives a placebo. After a few days on the medicine, each group is interviewed and asked how they would rate their comfort level 1-10 (1 being the most uncomfortable and 10 being no discomfort at all). The results are below. Find the 95% confidence interval in the difference of the mean comfort level. Is there sufficient evidence to conclude that the new medicine is effective? Assume the data is normally distributed with unequal variances. (Round answers to 4 decimal places) Make sure you put the 0 in front of the decimal. Average Group 1 = 5.84, SD Group 1 = 2.211334, n1 = 25 Average Group 2 = 3.96, SD Group 2 = 2.35372, n2 = 25arrow_forwardIn a randomized clinical trial, 888 people were placed given Drug A and 930 were given Drug B. The researcher's goals were to determine which drug had better efficacy against T.B. Of those who were given Drug A, 300 contracted T.B. Of the subjects who were given Drug B, 500 contracted T.B. Calculate and interpret the risk ratio of Drug B compared to Drug A for getting T.B.? 10. In Box City, an influenza vaccine was tested on 1,000 people, 400 males and 600 females. Of the males, 50% contracted influenza after vaccination versus 30% of the females. Calculate and interpret the risk ratio of females compared to males of contracting influenza. 11.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Glencoe Algebra 1, Student Edition, 9780079039897...AlgebraISBN:9780079039897Author:CarterPublisher:McGraw HillBig Ideas Math A Bridge To Success Algebra 1: Stu...AlgebraISBN:9781680331141Author:HOUGHTON MIFFLIN HARCOURTPublisher:Houghton Mifflin HarcourtHolt Mcdougal Larson Pre-algebra: Student Edition...AlgebraISBN:9780547587776Author:HOLT MCDOUGALPublisher:HOLT MCDOUGAL
- College Algebra (MindTap Course List)AlgebraISBN:9781305652231Author:R. David Gustafson, Jeff HughesPublisher:Cengage Learning
Glencoe Algebra 1, Student Edition, 9780079039897...
Algebra
ISBN:9780079039897
Author:Carter
Publisher:McGraw Hill
Big Ideas Math A Bridge To Success Algebra 1: Stu...
Algebra
ISBN:9781680331141
Author:HOUGHTON MIFFLIN HARCOURT
Publisher:Houghton Mifflin Harcourt
Holt Mcdougal Larson Pre-algebra: Student Edition...
Algebra
ISBN:9780547587776
Author:HOLT MCDOUGAL
Publisher:HOLT MCDOUGAL
College Algebra (MindTap Course List)
Algebra
ISBN:9781305652231
Author:R. David Gustafson, Jeff Hughes
Publisher:Cengage Learning
Sampling Methods and Bias with Surveys: Crash Course Statistics #10; Author: CrashCourse;https://www.youtube.com/watch?v=Rf-fIpB4D50;License: Standard YouTube License, CC-BY
Statistics: Sampling Methods; Author: Mathispower4u;https://www.youtube.com/watch?v=s6ApdTvgvOs;License: Standard YouTube License, CC-BY