Concept explainers
A.
To determine: The kinds of cation channels that respond to acetylcholine shown by patch-clamp measurements in the young rat muscles (Fig. Q11-4).
Concept introduction: Neurotransmitter is a chemical messenger that binds to the receptors present on the postsynaptic neuron. Acetylcholine is a neurotransmitter that utilizes its action on the cell by binding and activating receptors present on the surface of cells. It works through acetylcholine-gated cation channels at the neuromuscular junction. These channels open in response to acetylcholine secreted by the nerve terminal and Na+ ions enter the muscle cell causing membrane depolarization. This results in contraction of muscles.
B.
To calculate: The number of ions that enter in one millisecond for each kind of channel.
Concept introduction: Neurotransmitter is a chemical messenger that binds to the receptors present on the postsynaptic neuron. Acetylcholine is a neurotransmitter that utilizes its action on the cell by binding and activating receptors present on the surface of cells. It works through acetylcholine-gated cation channels at the neuromuscular junction. These channels open in response to acetylcholine secreted by the nerve terminal and Na+ ions enter the muscle cell causing membrane depolarization. This results in contraction of muscles.
Want to see the full answer?
Check out a sample textbook solutionChapter 11 Solutions
Molecular Biology of the Cell (Sixth Edition)
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education