Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)
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Chapter 12, Problem 10TYU

SCIENTIFIC INQUIRY

DRAW IT Assume you are mapping genes A, B, C, and D in Drosophila. You know that these genes are linked on the same chromosome, and you determine the recombination frequencies between each pair of genes to be as follows: A and B, 8%; A and C, 28%; A and D, 25%; 8 and C, 20%, B and D, 33%.

  1. a. Describe how you determined the recombination frequency for each pair of genes.
  2. b. Draw a chromosome map based on your data.
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In the diagram in the box below the horizontal line represents a chromosome and A, B, C, D and E represent the position of genes on the chromosome. You would expect the highest frequency of recombination of genes to occur between? A BC D E Lll S a) Between genes B and D b) Between genes B and C c) Between genes A and B d) Between genes A and C
In a series of mapping experiments, the recombination frequencies for four different linked genes of the Drosophila fly were determined, as shown in the figure. Based on this information, what is the most probable order of these genes on the chromosome? b 0 cn 90 rb 3.5 6.5 0 vg 19 9.0 16 0 b cn rb vg The numbers in the boxes are the recombination frequencies in between the genes (in percent). O b-rb-cn-vg O vg-cn-b-rb Orb-cn-vg-b b = black body cn = cinnabar eyes rb = reduced bristles vg = vestigial wings O vg-b-rb-cn
Drosophila geneticists made the first genetic maps. They claimed that the gene loci that they mapped “behaved mathematically as though they were in linear order” in the genetic material. They did not claim that these loci were actually physically located in a line along the chromosome. 1. Given what was known about chromosomes and the genetic material at that time, are these statements correct? Why or why not?

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Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)

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