Campbell Biology: Custom Edition
18th Edition
ISBN: 9781323717271
Author: Urry, Cain, Wasserman, Minorsky, Reece
Publisher: PEARSON C
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Textbook Question
Chapter 12, Problem 14TYU
SYNTHESIZE YOUR KNOWLEDGE
For selected answers, see Appendix A.
Shown here are two HeLa cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cells like these is misregulated. Identify genetic and other changes that might have caused these cells to escape normal cell cycle regulation.
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Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations.
The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene?
Inhibit cell growth and division
Oncogene
Inhibit apoptosis
Metabolic enzyme
EXPLAIN in 1-2 sentences:
A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation?
an activating mutation in a tumor suppressor gene
an activating mutation in a proto-oncogene
a loss of function mutation in a tumor suppressor gene
a loss of function mutation in a proto-oncogene
EXPLAIN in 1-2 sentences:
In an otherwise normal cell, what would be the immediate result of a…
Can you please answer the following three questions (one paragraph for each question). Your answers need to be in your own words. Please make sure everything is from your own words
1. In a paragraph, explain what is cancer?
2. In a paragraph, explain why cancer exists, what causes it, and other important things that relates to cancer in general?
3. In a paragraph, explain how different cancers affect different population? Explain also the stages of cancer
Remember your work should be in your own words. For anything you use, please cite it in APA.
Chapter 12 Solutions
Campbell Biology: Custom Edition
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
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