CAMPBELL'S BIOLOGY 12E PERUSALL
12th Edition
ISBN: 9780135858080
Author: Urry
Publisher: PERUSALL
expand_more
expand_more
format_list_bulleted
Textbook Question
Chapter 12, Problem 14TYU
SYNTHESIZE YOUR KNOWLEDGE
For selected answers, see Appendix A.
Shown here are two HeLa cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cells like these is misregulated. Identify genetic and other changes that might have caused these cells to escape normal cell cycle regulation.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Answer each question with a paragraph; 3-5 sentences each.
Explain the difference between a proto-oncogene and a tumor-suppressor gene.
Explain the difference between prokaryotic and eukaryotic cell division.
Explain the difference between positive regulation of the cell cycle and negative regulation of the cell cycle.
Explain the difference between normal p53 and mutated p53.
Find two differences and two similarities between binary fission and mitosis.
O Tumors of the blood
A tumor with limited growth
Explain why radiation and 5-fluorouracil are effective cancer treatments.
Please include a few sentences about how these treatments interact with
the cell cycle.
Your answer
Any comments please use this space (e.g. to clarify an answer or point o
issues on questions, etc.)
1.) Download an article related to on how Cancer Develops, how cancer affects cell cycle.
2.) Discuss your article and provide references. (not more than 250 words)
3.)Discuss your views on how to prevent cancer. (not more than 250 words)
Chapter 12 Solutions
CAMPBELL'S BIOLOGY 12E PERUSALL
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
Additional Science Textbook Solutions
Find more solutions based on key concepts
Identify each of the following reproductive barriers as prezygotic or postzygotic. a. One lilac species lives o...
Campbell Essential Biology with Physiology (5th Edition)
More than one choice may apply. Using the terms listed below, fill in the blank with the proper term. anterior ...
Essentials of Human Anatomy & Physiology (12th Edition)
2. Define equilibrium population. Outline the conditions that must be met for a population to stay in genetic e...
Biology: Life on Earth
The pedigrees indicated here were obtained with three unrelated families whose members express the same disease...
Genetics: From Genes to Genomes
Match the people in column A to their contribution toward the advancement of microbiology, in column B. Column ...
Microbiology: An Introduction
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Can you please answer the following three questions (one paragraph for each question). Your answers need to be in your own words. Please make sure everything is from your own words 1. In a paragraph, explain what is cancer? 2. In a paragraph, explain why cancer exists, what causes it, and other important things that relates to cancer in general? 3. In a paragraph, explain how different cancers affect different population? Explain also the stages of cancer Remember your work should be in your own words. For anything you use, please cite it in APA.arrow_forwardA 6-year old Caucasian girl from northern Europe, with a family history of melanoma, has recently relocated with her family to a small town near Brisbane, Australia. Discuss the environmental, lifestyle and genetic factors that could determine the girl’s susceptibility to cancer. Include in your answer how these factors can produce chromosomal or genetic alterations and the genetic steps that would result in metastatic melanoma, focusing on the classes of cancer genes involved in these processesarrow_forwardp53 is a gene / protein often associated with cancer. Why? What does p53 do? What kind of gene is it? Is it associated more with any one particular type of cancer or all cancers? Tell me more about p53, but please do not exceed one typed page.arrow_forward
- The chapter points out that about one of every five women and one of every four men in the United States will die from cancer. Why arerates of death from cancer different in men and women? Provide some possible explanations. 3. A couple has one child with bilateral retinoblastoma. The mother is free from cancer, but the father has unilateral retinoblastoma and he has a brother who has bilateral retinoblastoma. a. If the couple has another child, what is the probability that this next child will have retinoblastoma? b. If the next child has retinoblastoma, is it likely to be bilateral or unilateral? c. Explain why the father’s case of retinoblastoma is unilateral, whereas his son’s and brother’s cases are bilateralarrow_forwardQuestion 1. Describe and explain the epidemiological evidence supporting the view that cancer develops through a multi-step process involving increasingly severe stages.. Question 2. Describe and explain the genetic evidence supporting the view that cancer develops through a multi-step process involving increasingly severe stages.arrow_forwardLooking at Figure 1, what did Romansik et al. (2007) find regarding the relationship between the mitotic index and tumor grades. Explain their findings in your own words. Use specific details from Figure 1. The research paper is here: https://journals.sagepub.com/doi/10.1354/vp.44-3-335arrow_forward
- Match the following terms with their definition. Note that some of the terms will not be used. 1. S phase 2. Oncogene 3. G0 phase 4. Cyclin 5. Metaphase checkpoint 6. G2 phase 7. G1 checkpoint 8. Cyclin-dependent kinase 9. Mitosis ______The stage a cell is in if it is not going to divide ______The part of the cell cycle during which newly replicated DNA is checked for mistakes ______The part of the cell cycle during which DNA replication occurs ______An enzyme that adds phosphate groups to other proteins only when it is bound to another protein ______A protein that is present at high levels only during certain times of the cell cycle _____Point at which the cell dies if all the chromosomes are not correctly attached to the mitotic spindlearrow_forwardAnswer the following multiple-choice questions about cancer-promoting mutations. A gene whose mutant alleles function in a recessive way to predispose an individual’s cells to develop into cancer is called: A. a polymerase B. a proto-oncogene C. a tumor suppressor D. an oncogene EXPLAIN in 1-2 sentences:arrow_forwardDiscussion: (1 or 2 paragraphs with your own opinion like how Circulating Tumor DNA as Biomarkers for Cancer Detection technology can be early detector of cancer)arrow_forward
- Although cancer is not a contagious disease in humans or other vertebrates, there have been rare cases in which cancers have spread from one organism to another. Describe three cases of these contagious cancers and what conditions might have led to their appearance. For an introduction to this topic, see http:// www.cancer.org/cancer/cancerbasics/is-cancer-contagious.arrow_forwardD Question 18 Your patient's biopsy report indicates they have "cancer in situ". This means: Abnormal cells are present, they have not invaded local cells O Cells are normal, they will become cancer cells in the near future Abnormal cells are present, they have invaded a small number of local cells Cells are normal, they will not become cancer cells unless stimulated « Previousarrow_forwardOut of these 8 hallmarks ( sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, deregulating cellular energetics and metabolism, and avoiding immune destruction). Rank them from least important to most for cancer development. Explain in 2-3 sentences how.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license