Genetic Analysis: An Integrated Approach (2nd Edition)
Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 12, Problem 22P
Summary Introduction

To analyze:

Does homologous recombination always result in the formation of Heteroduplex DNA? Why or Why not?

Introduction:

Heteroduplex is a double-stranded DNA molecule of nucleic acids that result from a genetic recombination between single complementary strands of different homologous chromosomes or could be from dissimilar organisms.

In meiosis, the crossover happens between two non-sister chromatids that contributes forincrease in different allelic combinations and gametes.

The tetrad formation in Prophase - I of meiosis I explains this process that shows the breaking of the sister chromatid strand and formation of Holiday-junction.

A source of small RNAs (miRNAs, siRNAs, etc.) is Heteroduplex DNA, that play vital roles in post-transcriptional silencing.

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Students have asked these similar questions
What is homologous recombination?
Why is the term “crossing-over” appropriate for the exchange of DNA segments between homologous chromosomes?
Why is the upper limit of recombination 50% rather than 100%?

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Genetic Analysis: An Integrated Approach (2nd Edition)

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genetic recombination strategies of bacteria CONJUGATION, TRANSDUCTION AND TRANSFORMATION; Author: Scientist Cindy;https://www.youtube.com/watch?v=_Va8FZJEl9A;License: Standard youtube license