Concept explainers
To analyze:
Does homologous recombination always result in the formation of Heteroduplex DNA? Why or Why not?
Introduction:
Heteroduplex is a double-stranded DNA molecule of
In meiosis, the crossover happens between two non-sister chromatids that contributes forincrease in different allelic combinations and gametes.
The tetrad formation in Prophase
A source of small RNAs (miRNAs, siRNAs, etc.) is Heteroduplex DNA, that play vital roles in post-transcriptional silencing.
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Genetic Analysis: An Integrated Approach (2nd Edition)
- What is the name of the process in which a single strand of DNA disrupts a homologous dsDNA molecule and forms base pairs with one of the strands of this dsDNA molecule? During the recombination process does the single-stranded DNA molecule have a free 5' end, 3' end, or either?”arrow_forwardWhat do you mean by genetic recombination?arrow_forwardTwo loci exhibit 5% recombination between them. How many map units apart are they?arrow_forward
- What are recombinant chromosomes? How do they differ from the original chromosomes from which they are derived?arrow_forwardWhat are the two types of recombination? What are the details of eachtype? What components are needed for each type?arrow_forwardAn individual is heterozygous for a reciprocal translocation, with the following chromosomes: A • B C D E F A • B C V W X R ST • U D E F R ST • U V W X Q. Draw the products of alternate, adjacent-1, and adjacent-2 segregations.arrow_forward
- Describe two forms of genetic recombination. What functions do they fulfill?arrow_forwardCompare and contrast conjugation, transduction, and transformation. Which processes, if any, involve homologous recombination and which, if any, do not?arrow_forwardIn a germline progenitor cell before DNA replication (2N), a translocation occurred between a telocentric and submetacentric chromosome resulting in a translocation heterozygote. The location of the translocation is illustrated below. Draw the Prophase I pairing conformation that would result from this translocation. The four types of chromosomes you have now can be labeled as follows: T-WT (telocentric wild type), T-TL (telocentric translocation), SM-WT (submetacentric wild type), and SM-TL (submetacentric translocation). Using these labels, list (please do not draw) the possible outcomes of Anaphase I and the possible phenotypes for each outcome. Please explain your reasoning for each phenotype in a few words. asaparrow_forward
- What is difference between anonymous DNA polymorphisms and nonanonymous DNA polymorphisms?arrow_forwardDo homologous chromosomes have the same exact NUCLEOTIDE sequences? Why do we only need 23 chromosomes for DNA sequencing, when the two homologous pairs do not have the exact same nucleotide sequences? Why don't we use all 46 chromosomes?arrow_forwardIn some organisms, UV-induced thymine dimers can be repaired by photoreactivation, in which energy from visible light is used to split the bonds forming the cyclobutane ring ? true or false Non-homologous end joining occurs when enzymes cut out a few nucleotides around a double strand DNA break, and then fuse the ends back together (right) true or false?arrow_forward
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