EBK CAMPBELL BIOLOGY
11th Edition
ISBN: 8220103613828
Author: Reece
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 2TYU
Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to
- (A) disruption of mitotic spindle formation.
- (B) suppression of cyclin production.
- (C) myosin denaturation and inhibition of cleavage furrow formation.
- (D) inhibition of DNA synthesis.
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Chapter 12 Solutions
EBK CAMPBELL BIOLOGY
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
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- Part A and B A. What below would be likely to lead to cancer development? A) Overexpression of a cell cycle checkpoint inhibitor B) Loss of expression of a growth factor that promotes cell cycle entry C) Overexpression of a receptor tyrosine kinase that promotes cell cycle entry D) Overexpression of a DNA damage repair enzyme E) Loss of expression of a regulatory transcription factor that activates transcription of a cyclin B. Taxols inhibit the proper function of microtubules and are frequently used as chemotherapy drugs. What is the function of microtubules during the cell cycle? A) They promote the G1 to S checkpoint B) They normally inhibit M phase from being completed C) They form the mitotic spindle E) They mediate DNA replication F) They form the cleavage furrow during cytokinesisarrow_forwardWhich of the following is true with respect to cyclins and CDKs? A) CDKs promote progression of the cell cycle, cyclins function to inhibit progression of the cell cycle B) CDKs are the checkpoints in the cell cycle, and when bound to cyclins, they stop progression of the cell cycle C) CDKs will only work to promote progression of the cell cycle when complexed with their designated cyclins D) CDKs are rarely expressed during a cell's cycle, unless cyclins are present to act as transcription factors .arrow_forwardWhy is p53 considered a tumor suppressor protein? Question 12 options: a) Because p53 normally detects breaks in DNA. b) Because p53 normally causes progression from G1 to S phase to halt until damaged DNA is fully repaired. c) Because p53 normally repairs breaks in DNA. d) Because p53 normally stimulates transcription of Repair Polymerase. e) Because p53 normally reduces the mutation rate of DNA polymerase.arrow_forward
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