Cambell Biology 11e Vol1 For Utah Valley University Ch 1-25
11th Edition
ISBN: 9781323691519
Author: Urry
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 12, Problem 2TYU
Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to
- (A) disruption of mitotic spindle formation.
- (B) suppression of cyclin production.
- (C) myosin denaturation and inhibition of cleavage furrow formation.
- (D) inhibition of DNA synthesis.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Some cancer drugs stop cell division by stabilizing microtubules so they cannot come apart. Which step of the mitosis is disrupted?
A) Telophase
B) cytokinesis
C) Anaphase
D) Metaphase
Q49
When some cancer cells produce growth factors that stimulate their own division leading to continuous self-
stimulation for cell division it is referred to as
a) TNF tumor necrosis factor
b) AGS autocrine growth stimulation
Chapter 12 Solutions
Cambell Biology 11e Vol1 For Utah Valley University Ch 1-25
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
Additional Science Textbook Solutions
Find more solutions based on key concepts
How does trandlation differ from transcription?
Microbiology: Principles and Explorations
Explain why hyperthermophiles do not cause disease in humans.
Microbiology with Diseases by Taxonomy (5th Edition)
2. Why is it that the range of resting blood pressures of humans is best represented by a bell-shaped curve co...
Human Biology: Concepts and Current Issues
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Part A and B A. What below would be likely to lead to cancer development? A) Overexpression of a cell cycle checkpoint inhibitor B) Loss of expression of a growth factor that promotes cell cycle entry C) Overexpression of a receptor tyrosine kinase that promotes cell cycle entry D) Overexpression of a DNA damage repair enzyme E) Loss of expression of a regulatory transcription factor that activates transcription of a cyclin B. Taxols inhibit the proper function of microtubules and are frequently used as chemotherapy drugs. What is the function of microtubules during the cell cycle? A) They promote the G1 to S checkpoint B) They normally inhibit M phase from being completed C) They form the mitotic spindle E) They mediate DNA replication F) They form the cleavage furrow during cytokinesisarrow_forward3) Examine the graph showing the relative percentage normal and cancer cells spend in various stages of the cell cycle. Based on the information in the graphs, infer how cancer cells differ from typical, noncancerous cells. Select ALL that apply. A) Cancer cells do not replicate their DNA. B) Cancer cells replicate their DNA too quickly. C) Cancer cells do not go through interphase during their cell cycle. D) Cancer cells spend more time dividing compared to typical cells. E) Cancer cells do not always grow to the same size as typical cells. more than 1 answer. not gradedarrow_forwardWhich of the following is true with respect to cyclins and CDKs? A) CDKs promote progression of the cell cycle, cyclins function to inhibit progression of the cell cycle B) CDKs are the checkpoints in the cell cycle, and when bound to cyclins, they stop progression of the cell cycle C) CDKs will only work to promote progression of the cell cycle when complexed with their designated cyclins D) CDKs are rarely expressed during a cell's cycle, unless cyclins are present to act as transcription factors .arrow_forward
- Which of the following regarding microtubules is LEAST correct? A)Microtubules do not have important functions in neurons B)Microtubules are important for anterograde axoplasmic transport C)No answer text provided. D)Microtubules are important for maintaining the structure of the neuron E)Microtubules are important for retrograde axoplasmic transportarrow_forwardWhy is p53 considered a tumor suppressor protein? Question 12 options: a) Because p53 normally detects breaks in DNA. b) Because p53 normally causes progression from G1 to S phase to halt until damaged DNA is fully repaired. c) Because p53 normally repairs breaks in DNA. d) Because p53 normally stimulates transcription of Repair Polymerase. e) Because p53 normally reduces the mutation rate of DNA polymerase.arrow_forward(46) A mutated form of protein pox is found in patients with squamous cell carcinoma. In vitro studies show that the normal p5x molecule binds to DNA, and neoplastic cells accumulate in the G0 phase of the cell cycle. In contrast, the mutated form of p5x does not bind to DNA. These finding are most characteristics of which of the following? (A) Growht factor receptors (B) GTP-binding protein (C) Nonreceptor tyrosine kinases (D) Oncogene proteins (E) Tumor suppressor gene proteinsarrow_forward
- Biopsies from aggressive cancers often have cells that contain several nuclei per cell when viewed through a microscope. Which scenario could explain how such a multinucleated cell might have come to be? (a) The cell underwent repeated mitosis with simultaneous cytokinesis. (b) The cell had multiple S phases before it entered mitosis. (c) The cell underwent repeated mitosis, but cytokinesis did not occur. (d) The cell underwent repeated cytokinesis but no mitosis. (e) The cell actually went through meiosis and not mitosis.arrow_forwardAn example of a cell differentiation might include A) A cell traveling to its ultimate destination in the developing body B) Embryonic stem cells changing into liver and kidney cells C) Division of a zygote into many cells, all containing genetic material D) Unused neurons getting pruned awayarrow_forwardTelophase in Mitosis a ) Chromosomes begin to uncoil into chromatin. b) Nucleolus and nuclear membrane begin to reappear. c) Spindle slowly dissolves. d) In animal cells, cytokinesis occurs with a cleavage furrow dividing one cell into two cells. e) In plant cells, cytokinesis occurs with the formation of a cell plate. This plate divides the original cell into two cells and is part of the new cell wall.arrow_forward
- Please select correct onearrow_forwardNeed help If the mitotic spindle does not correctly attach to chromosome kinetochores, the spindle assembly checkpoint will be activated. Select all correct outcomes for chromosomes not correctly attached to mitotic spindle A) centrosome duplication will not occur B) M cyclin will be degraded C) APC will be inhibited D) chromosomes will not segregate E) Mad2 will bind to unattached kinetochores F) mitosis will halt at metaphase/anaphase transitionarrow_forward1) capZ encourages the elongation of actin filaments (true or false) 2)microtubules are tissue specific (true or false ) 3) microtubule-associated proteins stabilize microtubules along their length (true or false)arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license