ETEXT CAMPBELL BIOLOGY IN FOCUS INSTANT
ETEXT CAMPBELL BIOLOGY IN FOCUS INSTANT
3rd Edition
ISBN: 9780135964422
Author: Urry
Publisher: PEARSON
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Chapter 12, Problem 6TYU

You design Drosophila crosses to provide recombination data for gene a, which is located on the chromosome shown in Figure 12.12. Gene a has recombination frequencies of 14% with the vestigial-wing locus and 26% with the brown-eye locus. Approximately where is gene a located along the chromosome?

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Assume you are mapping genes A, B, C, and D in Drosophila. You know that these genes are linked on the same chromosome, and you determine the recombination frequencies between each pair of genes to be as follows: A–B, 8%; A– C, 28%; A–D, 25%; B–C, 20%; B–D, 33%. (a) Describe how you determined the recombination frequency for each pair of genes. (b) Draw a chromosome map based on your data.
The genetic map was based on crosses in Drosophila involving the three sex-linked genes a, b and c. “a” gives red eyes, “b” gives normal wings and “c” gives black body. The recombination frequencies between these genes are as follows; a and b is 23.8, b and c is 2.6 and a and c is 28.1, respectively.  Could you draw a basic genetic map based on distance between these genes using dots to show distance(s)? Could you make one fundamental comment using these distances based on genetic linkage?
In a series of mapping experiments, the recombination frequencies for four different linked genes of the Drosophila fly were determined, as shown in the figure. Based on this information, what is the most probable order of these genes on the chromosome? b 0 cn 90 rb 3.5 6.5 0 vg 19 9.0 16 0 b cn rb vg The numbers in the boxes are the recombination frequencies in between the genes (in percent). O b-rb-cn-vg O vg-cn-b-rb Orb-cn-vg-b b = black body cn = cinnabar eyes rb = reduced bristles vg = vestigial wings O vg-b-rb-cn

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ETEXT CAMPBELL BIOLOGY IN FOCUS INSTANT

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