Introduction:
The synaptic transmission or neurotransmission is a process by which neurotransmitters (signaling molecules) are released by the presynaptic neuron. Turning off the stimulus on time is also important like stimulating a postsynaptic cell. If not, the postsynaptic cell could continue to fire indefinitely, leading to changes in physiological coordination. So a molecule of a neurotransmitter binds only for 1 ms or so to its receptor, then separates from it. The two ways to stop the transmission process are stopping the neurotransmitter and removing the one which is already available. The former is achieved by cessation of signals in the presynaptic nerve fibers. The second is attained by neurotransmitter degradation, reuptake, and diffusion.
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Anatomy & Physiology: The Unity of Form and Function
- Briefly describe, in the correct sequence, the events thatoccur in synaptic transmission.arrow_forwardDiscuss the mechanisms on how to stop the signal in synaptic transmission.arrow_forwardWhich of the following statements concerning synapses is FALSE? O A) Modulation of synaptic strength can be presynaptic of postsynaptic B) High frequency stimulation in the presynaptic neuron often leads to DECREASED neurotransmitter release O C) Modulation of synaptic strength can either be short term, lasting seconds, or long term, lasting as long as a lifetime. D) Agonists are drugs that mimic neurotransmitters and antagonists are drugs that block the action of neurotransmitters O E) Certain drugs prevent the reuptake of neurotransmitter from the synapsearrow_forward
- Which types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forwardList the factors that determine Synaptic Strength?arrow_forwardlist at least eight ways in which the effectiveness of synapses may be altered and explain each pointarrow_forward
- Describe how synaptic events are integrated and modified.arrow_forwardHow is synaptic transmission terminated?arrow_forwardWhich of the following statements does not accurately describe a synapses? A) Both chemical and electrical synapses relay information through similar mechanisms. B) Both chemical and electrical synapses relay information from neurons to target cells. C) Electrical synapses have no gaps between the neuron and target cell. D) Chemical synapses have a gap between the neuron and target cell.arrow_forward
- Identify effects of chemicals (e.g. alcohol, caffeine, heroin) on synaptic transmissionarrow_forwardWhat does the statement "synaptic transmission is quantal" mean? Provide three lines of evidence that support the statement. Edit mo Tabloarrow_forwardWhich of the following is the role of axonal Calcium (Ca2+) channels in neuronal communication at the synapse? a) they inhibit the action potential causing it to stop b) Calcium channels have no role in this process c) by allowing calcium to exit the cell, they promote the propagation of action potential across the synapse by creating depolarization d) by blocking calcium entrance, they mediate the contraction of presynaptic axon to facilitate movement e) when they open, calcium enters the presynaptic terminal, promoting fusion of neurotransmitter vesicles with presynaptic membrane, and release of neurotransmitters to the synaptic cleftarrow_forward
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning