EBK BIOSTATISTICS FOR THE BIOLOGICAL AN
2nd Edition
ISBN: 9780134679228
Author: ROY
Publisher: PEARSON CUSTOM PUB.(CONSIGNMENT)
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 1.3, Problem 37SLCT
To determine
To explain: The meaning of the terms prospective, randomized, double-blind, place-controlled trial in the context of the provided study.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Dark Chocolate for Good Health
A study¹ examines chocolate's effects on blood vessel function in healthy people. In the randomized, double-blind, placebo-controlled
study, 11 people received 46 grams (1.6 ounces) of dark chocolate (which is naturally flavonoid-rich) every day for two weeks, while a
control group of 10 people received a placebo consisting of dark chocolate with low flavonoid content. Participants had their vascular
health measured (by means of flow-mediated dilation) before and after the two-week study. The increase over the two-week period
was measured, with larger numbers indicating greater vascular health. For the group getting the good dark chocolate, the mean
increase was 1.3 with a standard deviation of 2.32, while the control group had a mean change of -0.96 with a standard deviation of
1.58.
¹Engler, M., et. al., "Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in
healthy adults," Journal of the…
Current Attempt in Progress
Dark Chocolate for Good Health
A study examines chocolate's effects on blood vessel function in healthy people. In the randomized, double-blind, placebo-
controlled study, 11 people received 46 grams (1.6 ounces) of dark chocolate (which is naturally flavonoid-rich) every day for two
weeks, while a control group of 10 people received a placebo consisting of dark chocolate with low flavonoid content. Participants
had their vascular health measured (by means of flow-mediated dilation) before and after the two-week study. The increase over
the two-week period was measured, with larger numbers indicating greater vascular health. For the group getting the good dark
chocolate, the mean increase was 1.3 with a standard deviation of 2.32, while the control group had a mean change of-0.96 with a.
standard deviation of 1.58.
"Engler, M., et. al., "Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in
healthy…
Stressed-Out Bus Drivers. Previous studies have shown that urban bus drivers have an extremely stressful job, and a large proportion of drivers retire prematurely with disabilities due to occupational stress. In the paper, “Hassles on the Job: A Study of a Job Intervention With Urban Bus Drivers” (Journal of Organizational Behavior, Vol. 20, pp. 199–208), G. Evans et al. examined the effects of an intervention program to improve the conditions of urban bus drivers.Amongother variables, the researchers monitored diastolic blood pressure of bus drivers in downtown Stockholm, Sweden. The data, in millimeters of mercury (mm Hg), on the WeissStats site are based on the blood pressures obtained prior to intervention for the 41 bus drivers in the study. Use the technology of your choice to do the following.
a. Obtain a normal probability plot, boxplot, histogram, and stemand-leaf diagram of the data.
b. Based on your results from part (a), can you reasonably apply the one-mean t-test to the…
Chapter 1 Solutions
EBK BIOSTATISTICS FOR THE BIOLOGICAL AN
Ch. 1.1 - Prob. 1SLCTCh. 1.1 - Prob. 2SLCTCh. 1.1 - Prob. 3SLCTCh. 1.1 - Prob. 4SLCTCh. 1.1 - Prob. 5SLCTCh. 1.1 - Prob. 6SLCTCh. 1.1 - Prob. 7SLCTCh. 1.1 - Prob. 8SLCTCh. 1.1 - Prob. 9SLCTCh. 1.1 - Prob. 10SLCT
Ch. 1.1 - Prob. 11SLCTCh. 1.1 - Prob. 12SLCTCh. 1.1 - Prob. 13SLCTCh. 1.1 - Prob. 14SLCTCh. 1.1 - Prob. 15SLCTCh. 1.1 - Prob. 16SLCTCh. 1.1 - Prob. 17SLCTCh. 1.1 - Prob. 18SLCTCh. 1.1 - Prob. 19SLCTCh. 1.1 - Prob. 20SLCTCh. 1.1 - Prob. 21SLCTCh. 1.1 - Prob. 22SLCTCh. 1.1 - Prob. 23SLCTCh. 1.1 - Prob. 24SLCTCh. 1.1 - Prob. 25SLCTCh. 1.1 - Prob. 26SLCTCh. 1.1 - Prob. 27SLCTCh. 1.1 - Prob. 28SLCTCh. 1.1 - Prob. 29SLCTCh. 1.1 - Prob. 30SLCTCh. 1.1 - Prob. 31SLCTCh. 1.1 - Prob. 32SLCTCh. 1.2 - Prob. 1SLCTCh. 1.2 - Prob. 2SLCTCh. 1.2 - Prob. 3SLCTCh. 1.2 - Prob. 4SLCTCh. 1.2 - Prob. 5SLCTCh. 1.2 - Prob. 6SLCTCh. 1.2 - Prob. 7SLCTCh. 1.2 - Prob. 8SLCTCh. 1.2 - Prob. 9SLCTCh. 1.2 - Prob. 10SLCTCh. 1.2 - Prob. 11SLCTCh. 1.2 - Prob. 12SLCTCh. 1.2 - Prob. 13SLCTCh. 1.2 - Prob. 14SLCTCh. 1.2 - Prob. 15SLCTCh. 1.2 - Prob. 16SLCTCh. 1.2 - Prob. 17SLCTCh. 1.2 - Prob. 18SLCTCh. 1.2 - Prob. 19SLCTCh. 1.2 - Prob. 20SLCTCh. 1.2 - Prob. 21SLCTCh. 1.2 - Prob. 22SLCTCh. 1.2 - Prob. 23SLCTCh. 1.2 - Prob. 24SLCTCh. 1.2 - Prob. 25SLCTCh. 1.2 - Prob. 26SLCTCh. 1.2 - Prob. 27SLCTCh. 1.2 - Prob. 28SLCTCh. 1.2 - Prob. 29SLCTCh. 1.2 - Prob. 30SLCTCh. 1.2 - Prob. 31SLCTCh. 1.2 - Prob. 32SLCTCh. 1.2 - Prob. 33SLCTCh. 1.3 - Prob. 1SLCTCh. 1.3 - Prob. 2SLCTCh. 1.3 - Prob. 3SLCTCh. 1.3 - Prob. 4SLCTCh. 1.3 - Prob. 5SLCTCh. 1.3 - Prob. 6SLCTCh. 1.3 - Prob. 7SLCTCh. 1.3 - Prob. 8SLCTCh. 1.3 - Prob. 9SLCTCh. 1.3 - Prob. 10SLCTCh. 1.3 - Prob. 11SLCTCh. 1.3 - Prob. 12SLCTCh. 1.3 - Prob. 13SLCTCh. 1.3 - Prob. 14SLCTCh. 1.3 - Prob. 15SLCTCh. 1.3 - Prob. 16SLCTCh. 1.3 - Prob. 17SLCTCh. 1.3 - Prob. 18SLCTCh. 1.3 - Prob. 19SLCTCh. 1.3 - Prob. 20SLCTCh. 1.3 - Prob. 21SLCTCh. 1.3 - Prob. 22SLCTCh. 1.3 - Prob. 23SLCTCh. 1.3 - Prob. 24SLCTCh. 1.3 - Prob. 25SLCTCh. 1.3 - Prob. 26SLCTCh. 1.3 - Prob. 27SLCTCh. 1.3 - Prob. 28SLCTCh. 1.3 - Prob. 29SLCTCh. 1.3 - Prob. 30SLCTCh. 1.3 - Prob. 31SLCTCh. 1.3 - Prob. 32SLCTCh. 1.3 - Prob. 33SLCTCh. 1.3 - Prob. 34SLCTCh. 1.3 - Prob. 35SLCTCh. 1.3 - Prob. 36SLCTCh. 1.3 - Prob. 37SLCTCh. 1.3 - Prob. 38SLCTCh. 1 - Prob. 1CQQCh. 1 - Prob. 2CQQCh. 1 - Prob. 3CQQCh. 1 - Prob. 4CQQCh. 1 - Prob. 5CQQCh. 1 - Prob. 6CQQCh. 1 - Prob. 7CQQCh. 1 - Prob. 8CQQCh. 1 - Prob. 9CQQCh. 1 - Prob. 10CQQCh. 1 - Prob. 1RECh. 1 - Prob. 2RECh. 1 - Prob. 3RECh. 1 - Prob. 4RECh. 1 - Prob. 5RECh. 1 - Prob. 6RECh. 1 - Prob. 7RECh. 1 - Prob. 8RECh. 1 - Prob. 9RECh. 1 - Prob. 10RECh. 1 - Prob. 1CRECh. 1 - Prob. 2CRECh. 1 - Prob. 3CRECh. 1 - Prob. 4CRECh. 1 - Prob. 5CRECh. 1 - Prob. 6CRECh. 1 - Prob. 7CRECh. 1 - Prob. 8CRECh. 1 - Prob. 9CRECh. 1 - Prob. 10CRECh. 1 - Prob. 11CRECh. 1 - Prob. 12CRE
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, statistics and related others by exploring similar questions and additional content below.Similar questions
- Angioplasty is a medical procedure in which an obstructed blood vessel is widened. In some cases, a wire mesh tube, called a stent, is placed in the vessel to help it remain open. The article “Long-term Outcomes of Patients Receiving Drug-eluting Stents” (A. Philpott, D. Southern, et al., Canadian Medical Association Journal, 2009:167–174) presents the results of a study comparing the effectiveness of a bare metal stent with one that that has been coated with a drug designed to prevent reblocking of the vessel. A total of 5320 patients received bare metal stents, and of these, 841 needed treatment for reblocking within a year. A total of 1120 received drug coated stents, and 134 of them required treatment within a year. a) Find a 98% confidence interval for the differences between the proportions for drug coated stents and bare metal stents. b) Suppose that additional patients are to be treated in order to increase the precision of the confidence interval. Three sampling plans are…arrow_forwardCalcium and Blood Pressure Does increasing the amount of calcium in our diet reduce blood pressure? Examination of a large sample of people revealed a relationship between calcium intake and blood pressure. Such observational studies do not establish causation. Researchers therefore designed a randomized comparative experiment. The subjects were 21 healthy men who volunteered to take part in the experiment. They were randomly assigned to two groups: 10 of the men received a calcium supplement for 12 weeks, while the control group of 11 men received a placebo pill that looked identical. The experiment was double-blind. The response variable is the decrease in systolic (top number) blood pressure for a subject after 12 weeks, in millimeters of mercury. An increase appears as a negative number. Do the data provide convincing evidence that a calcium supplement reduces blood pressure more than a placebo, on average, for subjects like the ones in this study? Group 1 (calcium) Group (placebo)…arrow_forwardDexamethasone and IQ. In the paper “Outcomes at School Age After Postnatal Dexamethasone Therapy for Lung Disease of Prematurity” (New England Journal of Medicine, Vol. 350, No. 13, pp. 1304–1313), T. Yeh et al. studied the outcomes at school age in children who had participated in a double-blind, placebo-controlled trial of early postnatal dexamethasone therapy for the prevention of chronic lung disease of prematurity. One result reported in the study was that, at school age, the control group of 74 children had an average IQ score of 84.4, whereas the dexamethasone group of 72 children had an average IQ score of 78. a. experimental units. b. response variable. c. factor(s). d. levels of each factor. e. treatments.arrow_forward
- NCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…arrow_forwardDexamethasone and IQ. In the paper “Outcomes at School Age After Postnatal Dexamethasone Therapy for Lung Disease of Prematurity” (New England Journal of Medicine, Vol. 350, No. 13, pp. 1304–1313), T. Yeh et al. studied the outcomes at school age in children who had participated in a double-blind, placebo-controlled trial of early postnatal dexamethasone therapy for the prevention of chronic lung disease of prematurity. All of the infants in the study had had severe respiratory distress syndrome requiring mechanical ventilation shortly after birth. On the WeissStats site, we provide the school-age IQs of the 74 children in the control group, based on the study results. Use the technology of your choice to do the following. a. Obtain a normal probability plot, boxplot, histogram, and stemand-leaf diagram of the data. b. Based on your results from part (a), can you reasonably apply one-standard-deviation χ2-procedures to the data? Explain your reasoning. c. Overall, IQs of school-age…arrow_forwardNCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…arrow_forward
- NCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…arrow_forwardNCI Cancer Bulletin, December 2, 2008 Volume 5 / Number 24 Title of the article: After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use Women who are overweight or obese after menopause face an increased risk of breast cancer, but a large prospective cohort study indicates that the frequency of mammography use and screening accuracy are not the primary explanations for higher rates of breast cancer in these women. The same is true of large, invasive breast cancer tumors and advanced stage disease; risk increases with weight, but higher rates are not explained by the frequency or accuracy of screening mammography before breast cancer was diagnosed. The study appears in the December 3 Journal of the National Cancer Institute. Dr. Karla Kerlikowske of the San Francisco Veterans Affairs Medical Center and colleagues gathered data on 287,115 postmenopausal women who were registered in the Breast Cancer Surveillance Consortium database. Reflecting a trend in the…arrow_forwardTreating Psychotic Illness. L. Petersen et al. evaluated the effects of integrated treatment for patients with a first episode of psychotic illness in the paper “A Randomised Multicentre Trial of Integrated Versus Standard Treatment for Patients with a First Episode of Psychotic Illness” (British Medical Journal, Vol. 331, (7517):602). Part of the study included a questionnaire that was designed to measure client satisfaction for both the integrated treatment and a standard treatment. The data on the WeissStats site are based on the results of the client questionnaire. a. use the technology of your choice to obtain boxplots for the data sets, using the same scale. b. compare the data sets by using your results from part (a), paying special attention to center and variation.arrow_forward
- Neutropenia. Neutropenia is an abnormally low number of neutrophils (a type of white blood cell) in the blood. Chemotherapy often reduces the number of neutrophils to a level that makes patients susceptible to fever and infections. G. Bucaneve et al. published a study of such cancer patients in the paper “Levofloxacin to Prevent Bacterial Infection in Patients With Cancer and Neutropenia” (New England Journal of Medicine, Vol. 353, No. 10, pp. 977–987). For the study, 375 patients were randomly assigned to receive a daily dose of levofloxacin, and 363 were given placebo. In the group receiving levofloxacin, fever was present in 243 patients for the duration of neutropenia, whereas fever was experienced by 308 patients in the placebo group. a. At the 1% significance level, do the data provide sufficient evidence to conclude that levofloxacin is effective in reducing the occurrence of fever in such patients? b. Find a 98% confidence level for the difference in the proportions of such…arrow_forwardAn article describes several studies of the failure rate of defibrillators used in the treatment of heart problems. In one study conducted by the Mayo Clinic, it was reported that failures were experienced within the first 2 years by 11 of 93 patients under 50 years old and 14 of 354 patients ages 50 and older who received a particular type of defibrillator. Assume it is reasonable to regard these two samples as representative of patients in the two age groups who receive this type of defibrillator. n USE SALT (a) Construct a 95% confidence interval for the proportion of patients under 50 years old who experience a failure within the first 2 years after receiving this type of defibrillator. (Round your answers to three decimal places.) Interpret the interval. O we are 95% confident that the proportion of all patients under 50 years old who experience a failure within the first two years after receiving this type of defibrillator is within this interval. O we are confident that 95% of…arrow_forwardAVONEX and MS. An issue of Inside MS contained an article describing AVONEX (interferon beta-1a), a drug used in the treatment of relapsing forms of multiple sclerosis (MS). Included in the article was a report on “. . . adverse events and selected laboratory abnormalities that occurred at an incidence of 2% or more among the 158 multiple sclerosis patients treated with 30 mcg of AVONEX once weekly by IM injection.” In the study, 158 patients took AVONEX and 143 patients were given placebo. a. Is this study observational or is it a designed experiment?b. Identify the treatment group, control group, and treatmentsarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- MATLAB: An Introduction with ApplicationsStatisticsISBN:9781119256830Author:Amos GilatPublisher:John Wiley & Sons IncProbability and Statistics for Engineering and th...StatisticsISBN:9781305251809Author:Jay L. DevorePublisher:Cengage LearningStatistics for The Behavioral Sciences (MindTap C...StatisticsISBN:9781305504912Author:Frederick J Gravetter, Larry B. WallnauPublisher:Cengage Learning
- Elementary Statistics: Picturing the World (7th E...StatisticsISBN:9780134683416Author:Ron Larson, Betsy FarberPublisher:PEARSONThe Basic Practice of StatisticsStatisticsISBN:9781319042578Author:David S. Moore, William I. Notz, Michael A. FlignerPublisher:W. H. FreemanIntroduction to the Practice of StatisticsStatisticsISBN:9781319013387Author:David S. Moore, George P. McCabe, Bruce A. CraigPublisher:W. H. Freeman
MATLAB: An Introduction with Applications
Statistics
ISBN:9781119256830
Author:Amos Gilat
Publisher:John Wiley & Sons Inc
Probability and Statistics for Engineering and th...
Statistics
ISBN:9781305251809
Author:Jay L. Devore
Publisher:Cengage Learning
Statistics for The Behavioral Sciences (MindTap C...
Statistics
ISBN:9781305504912
Author:Frederick J Gravetter, Larry B. Wallnau
Publisher:Cengage Learning
Elementary Statistics: Picturing the World (7th E...
Statistics
ISBN:9780134683416
Author:Ron Larson, Betsy Farber
Publisher:PEARSON
The Basic Practice of Statistics
Statistics
ISBN:9781319042578
Author:David S. Moore, William I. Notz, Michael A. Fligner
Publisher:W. H. Freeman
Introduction to the Practice of Statistics
Statistics
ISBN:9781319013387
Author:David S. Moore, George P. McCabe, Bruce A. Craig
Publisher:W. H. Freeman
Statistics 4.1 Point Estimators; Author: Dr. Jack L. Jackson II;https://www.youtube.com/watch?v=2MrI0J8XCEE;License: Standard YouTube License, CC-BY
Statistics 101: Point Estimators; Author: Brandon Foltz;https://www.youtube.com/watch?v=4v41z3HwLaM;License: Standard YouTube License, CC-BY
Central limit theorem; Author: 365 Data Science;https://www.youtube.com/watch?v=b5xQmk9veZ4;License: Standard YouTube License, CC-BY
Point Estimate Definition & Example; Author: Prof. Essa;https://www.youtube.com/watch?v=OTVwtvQmSn0;License: Standard Youtube License
Point Estimation; Author: Vamsidhar Ambatipudi;https://www.youtube.com/watch?v=flqhlM2bZWc;License: Standard Youtube License