The mechanism of N-cadherin mediated neural proginator migration in the neocortex. Also explain the role of cell sorting in this migration, when the cell adhesion play a fundamental role in layering the cortex. Introduction: The presence of distinct neuronal layers is a specific characterstic of the mammalian neocortex. These neuronal layers are generated by the sequential migration of neurons which are in developing stage, along the neuroepithelial or radial glial cells. This migration is tightly regulated by a signalling mechanism present in developing neocortex. The cadherins are designated as a group of cell-cell adhesion molecules, which play an important role in a number of morphogenetic and pathological processes.

Question

Want to see the full answer?

Answer 1

Question

Chapter 14, Problem 3DQ

Summary Introduction

To review:

The mechanism of N-cadherin mediated neural proginator migration in the neocortex. Also explain the role of cell sorting in this migration, when the cell adhesion play a fundamental role in layering the cortex.

Introduction:

The presence of distinct neuronal layers is a specific characterstic of the mammalian neocortex. These neuronal layers are generated by the sequential migration of neurons which are in developing stage, along the neuroepithelial or radial glial cells. This migration is tightly regulated by a signalling mechanism present in developing neocortex. The cadherins are designated as a group of cell-cell adhesion molecules, which play an important role in a number of morphogenetic and pathological processes.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Project 2 Muscle Diseases: Muscular Dystrophy1Spunky is a 5-year-old girl who has very large calf muscles and shows severe weakness in her leg and armmuscles. Laboratory tests showed that Spunky has high levels of creatine phosphokinase in her urine. The doctor explained to her parents that Spunky!s muscles are being replaced by fat and connective tissue because her body cells cannot metabolize protein properly. As a result, Spunky!s cells cannot produce creatine from amino acids. Therefore, she cannot store creatine phosphate in her muscles that is necessary to provide energy for her muscles to contract. Help Spunky!s parents understand her disease by completing the following tasks.2. Write the origin and insertion point of each muscle.3. Draw a diagram to show how a muscle fiber uses energy for contraction.

NEED ASAP THANKS A 25-year-old G1P0 seeks consult at a Maternity Clinic. A non-stress test was requested by the attending physician. During the procedure, the tracing displays a relatively flat line for fetal movement, making it difficult to evaluate the fetal heart rate (FHR). To mark the strip, the nurse in charge should instruct the client to push the control button at which time? a. At the end of fetal movement b. At the beginning of each contraction c. At the beginning of each fetal movement d. After every three fetal movements

Q1: Multiple sclerosis is a demyelinating disease affecting the central nervous system. What type of cell would be the most likely target of this disease? Why? What is the normal function of this type of cell and what would be the consequence?