Nester's Microbiology: A Human Perspective
9th Edition
ISBN: 9781259709999
Author: Denise G. Anderson Lecturer, Sarah Salm, Deborah Allen
Publisher: McGraw-Hill Education
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Chapter 15, Problem 10MC
Summary Introduction
Introduction:
When an antigen enters the body, it is processed by the antigen presenting cells (APCs) and is expressed on the major histocompatibility complex (MHC) to be presented to the T cells for its further elimination. MHC has three classes: I, II, and III. MHC I molecules are present on all the nucleated cells and MHC II are present on APCs.
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What is the function of MHC? Which cells make MHC I, and which make MHC II? What WBCs can present antigens in MHC II?
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Chapter 15 Solutions
Nester's Microbiology: A Human Perspective
Ch. 15 - Prob. 1SACh. 15 -
2. Diagram an IgG molecule and label (a) the Fc...Ch. 15 -
3. Describe the protective outcomes of...Ch. 15 - Which antibody class is the first produced during...Ch. 15 - Prob. 5SACh. 15 - Prob. 6SACh. 15 -
7. How do T-independent antigens differ from...Ch. 15 -
8. What are antigen-presenting cells (APCs)?
Ch. 15 - Prob. 9SACh. 15 -
10. How does the role of natural killer cells...
Ch. 15 - The variable regions of antibodies are located in...Ch. 15 - Which of the following statements about antibodies...Ch. 15 - Which class of antibody can cross the placenta? a)...Ch. 15 - Prob. 4MCCh. 15 - Which of the following statements about B...Ch. 15 - Prob. 6MCCh. 15 - Prob. 7MCCh. 15 - Prob. 8MCCh. 15 - Prob. 9MCCh. 15 - Prob. 10MCCh. 15 - Prob. 1ACh. 15 -
2. What kinds of diseases would be expected to...Ch. 15 - Prob. 1CTCh. 15 - Prob. 2CT
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- Why are MHC proteins so highly variable?arrow_forwardWhat is the appropriate response when antigen is presented on MHC class II molecules?a) An effector CD8 cell should kill the presenting cell.b) An effector CD4 cell should kill the presenting cell.c) An effector CD8 cell should activate the presenting cell.d) An effector CD4 cell should activate the presenting cell.arrow_forwardHow does a single MHC protein present many differentpeptides to T cells?arrow_forward
- Distinguish between class I and class II MHC proteins.arrow_forwardWhat distinguishes MHC I from MHC II? a-aquisition of antigenic peptide in the cytoplasm b-cross-presentation of antigegn to CD4 T cells c- presentation of peptides to the T cell receptor d-binding of a B-amino acid peptide e- presentation of antigenic peptides to CD4 T cellsarrow_forwardWhat types of cells display MHC class I and class IIantigen complexes, and what happens as a result?arrow_forward
- In regard to antigen presentation, MHC class I molecules usually present peptides derived from _____, whereas MHC class II molecules usually present peptides derived from _____. a. intracellular cytosolic sources; vesicular system b. phagolysosome; proteasomes c. MIIC; self proteins d. CLIP; HLA-DM e. endocytic vesicles; endoplasmic reticulum.arrow_forwardHow is a B-cell receptor similar to an antibody?arrow_forwardMHC class I proteins: A. both are on all nucleated cells and present endogenous antigens to the immune system B. present endogenous antigens to the immune system C. are on all nucleated cellsarrow_forward
- What are chimeric antigen receptors, and how are they constructed?arrow_forwardHow is the newly emerging repertoire of T cells, with their diverse pre-TCRs, further differentiated so that a productive interaction with self-MHC–peptide complexes can occur?arrow_forwardWhat is Natural antibodies?arrow_forward
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