(a)
Interpretation:
Show how the gicven product can be synthesized from the Grignard reagent.
Concept introduction:
Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic
Addition of a Grignard reagent to an
Thus,
Reaction of Grignard reagent with formaldehyde yields primary alcohol. Secondary and tertiary alcohol can be prepared by the reaction of Grignard reagent with any aldehyde (except formaldehyde) and ketone respectively.
An equimolar mixture of the two enantiomers is called racemic mixture and it is optically inactive.
(b)
Interpretation:
Show how the gicven product can be synthesized from the Grignard reagent.
Concept introduction:
Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic chemical reaction in which the Grignard reagent act as nucleophile and attack electrophilic carbon atom that are present within polar bonds to yield a carbon-carbon bond.
Addition of a Grignard reagent to an aldehyde/ketone followed by protonation will produce an alcohol.
Thus,
Reaction of Grignard reagent with formaldehyde yields primary alcohol. Secondary and tertiary alcohol can be prepared by the reaction of Grignard reagent with any aldehyde (except formaldehyde) and ketone respectively.
An equimolar mixture of the two enantiomers is called racemic mixture and it is optically inactive.
(c)
Interpretation:
Show how the gicven product can be synthesized from the Grignard reagent.
Concept introduction:
Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic chemical reaction in which the Grignard reagent act as nucleophile and attack electrophilic carbon atom that are present within polar bonds to yield a carbon-carbon bond.
Addition of a Grignard reagent to an aldehyde/ketone followed by protonation will produce an alcohol.
Thus,
Reaction of Grignard reagent with formaldehyde yields primary alcohol. Secondary and tertiary alcohol can be prepared by the reaction of Grignard reagent with any aldehyde (except formaldehyde) and ketone respectively.
An equimolar mixture of the two enantiomers is called racemic mixture and it is optically inactive.
(d)
Interpretation:
Show how the gicven product can be synthesized from the Grignard reagent.
Concept introduction:
Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic chemical reaction in which the Grignard reagent act as nucleophile and attack electrophilic carbon atom that are present within polar bonds to yield a carbon-carbon bond.
Addition of a Grignard reagent to an aldehyde/ketone followed by protonation will produce an alcohol.
Thus,
Reaction of Grignard reagent with formaldehyde or oxirane yields primary alcohol. Secondary and tertiary alcohol can be prepared by the reaction of Grignard reagent with any aldehyde (except formaldehyde) and ketone respectively.
An equimolar mixture of the two enantiomers is called racemic mixture and it is optically inactive.
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Chapter 16 Solutions
Organic Chemistry
- Synthesize the products by drawing out reagents and intermediates along the way.arrow_forwardSynthesize the following compounds from the given starting material. You can add on any alkyl/ alkyl halide under 8 carbons or any necessary inorganic reagent needed (this includes triphenyl phosphine (Ph3P). Please draw all intermediates and reagents necessary to get to the productarrow_forwardProvide the appropriate reagent(s) for the following transformationarrow_forward
- Finish the indicated reaction by filling in and starting materials, reagents or products as needed arrow_forwardShow how you can synthesize the following compounds using the indicated starting materials and any other necessary substances or reagents.arrow_forwardDevise a synthesis for each compound, starting with methylenecyclohexane and any other reagents you need. cyclohexylmethanolarrow_forward
- Draw the major product of the reaction. OH NaH H2 NaBr + C6H100 DMF "Br +arrow_forwardWhich of the following reagents can do conjugate addition? NaOH LDA PhMgBr (CH3)CHOHarrow_forwardA) Show how the following compound can be synthesized from the indicated carbon sources (you may use any other solvents/reagents that you need). compounds containing 3 or fewer carbons ?arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning