Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 17, Problem 10P
Summary Introduction

To determine: How many cups of coffee is required to reach the dose of 10mM to interfere with the DNA damage response.

Introduction: The activity of the various inhibitory mechanisms provides information about the extracellular environment, cell damage, and incomplete cell-cycle events. The progression through the cell cycle is controlled by extracellular mitogens as well as intracellular signals. The most important influence of DNA damage occurs due to spontaneous chemical reactions in DNA, error in DNA replication, or exposure to certain chemicals. It is essential to attempt the repair of damaged DNA before its duplication or segregation.

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