How both the drugs taxol and colchicine are toxic to dividing cells. Concept introduction: Dynamic instability is the period of switching between phases of relatively slow growing and fast shortening at the ends of individual microtubules. It is a result of the hydrolysis of GTP-bound to β-tubulin shortly after assembly.

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 17, Problem 17Q

Summary Introduction

To explain: How both the drugs taxol and colchicine are toxic to dividing cells.

Concept introduction: Dynamic instability is the period of switching between phases of relatively slow growing and fast shortening at the ends of individual microtubules. It is a result of the hydrolysis of GTP-bound to β-tubulin shortly after assembly.

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Answer 2

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 17, Problem 17Q

Summary Introduction

To explain: How both the drugs taxol and colchicine are toxic to dividing cells.

Concept introduction: Dynamic instability is the period of switching between phases of relatively slow growing and fast shortening at the ends of individual microtubules. It is a result of the hydrolysis of GTP-bound to β-tubulin shortly after assembly.

Expert Solution & Answer

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Answer 3

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 17, Problem 17Q

Summary Introduction

To explain: How both the drugs taxol and colchicine are toxic to dividing cells.

Concept introduction: Dynamic instability is the period of switching between phases of relatively slow growing and fast shortening at the ends of individual microtubules. It is a result of the hydrolysis of GTP-bound to β-tubulin shortly after assembly.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 4

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 17, Problem 17Q

Summary Introduction