Essential Cell Biology (fifth Edition)
Essential Cell Biology (fifth Edition)
5th Edition
ISBN: 9780393680362
Author: ALBERTS, Bruce, Hopkin, Karen, Johnson -
Publisher: W. W. Norton & Company
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Chapter 17, Problem 2Q
Summary Introduction

To explain: The reason that it is much easier to add tubulin to existing microtubules than to start a new microtubule.

Introduction: The microtubules are hollow and cylindrical in structure. They are approximately 25 nm in diameter, present in all eukaryotic cells and play critical roles in the determination of cell shape and also in cellular motility. It is composed of α β-tubulin having two subunits such as α-tubulin and β-tubulin. The β-tubulin subunits are exposed at the plus ends and α-tubulin subunits are exposed at the minus ends. The microtubule organizing centre (MTOC) contains a proteins know as γ-tubulin that serve in the nucleation of microtubule formation.

Summary Introduction

To explain: How the γ-tubulin in the centrosome helps to overcome the above problem.

Introduction: The microtubules are hollow and cylindrical in structure. They are approximately 25 nm in diameter, present in all eukaryotic cells and play critical roles in the determination of cell shape and also in cellular motility. It is composed of αβ-tubulin having two subunits such as α-tubulin and β-tubulin. The β-tubulin subunits are exposed at the plus ends and α-tubulinsubunits are exposed at the minus ends. The microtubule organizing centre (MTOC) contains a proteins know as γ-tubulin that serve in the nucleation of microtubule formation.

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