To predict: The cellular response that would occur in response to high doses of a drug that binds to a specific hormone receptor.
Concept introduction: The endocrine glands are the ductless organs located within the organ systems and contain groups of endocrine cells that secrete their hormones directly into their surroundings. Hormones are the chemical messengers that are secreted by the endocrine system. The hormone receptors may be found in the plasma membrane or in the intracellular compartment of the target cell.
To explain: Whether more or less of the drug will be required for the down-regulation over time.
Concept introduction: The endocrine glands are the ductless organs located within the organ systems and contain groups of endocrine cells that secrete their hormones directly into their surroundings. Hormones are the chemical messengers that are secreted by the endocrine system. The hormone receptors may be found in the plasma membrane or in the intracellular compartment of the target cell.
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