To explain: The consequences and mechanism of the sudden increase and the decrease in the M cyclin concentration by the M-Cdk during the M phase.
Concept introduction: Cyclins are the regulatory part of the heterodimeric kinase involved in the cell cycle. Cyclin-dependent kinases (Cdks) are the catalytic part of the heterodimeric kinase. Each cell cycle phase has its own cyclin and associated Cdk. As the name suggests, the Cdk can act only when the cyclin is present. Therefore, the cell uses this as a regulatory mechanism to regulate the cell cycle mechanism. The Cdks are present in all phases, but the cyclins are produced only during the previous Gap phases and are immediately degraded once their work is done. The cyclin for M phase is Cyclin B, and the Cdk is Cdk 1. The Cyclins and Cdk are required to activate the corresponding cell cycle phase.
Want to see the full answer?
Check out a sample textbook solutionChapter 18 Solutions
Essential Cell Biology
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education