Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780134433769
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman
Publisher: PEARSON
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Chapter 18, Problem 2TYU
Summary Introduction
Introduction:
Homeotic gene is a gene used in regulation of various anatomical structures in organisms. It regulates growth of anatomical structure. Homeotic genes and other genes contain the homeobox domains which maintain the polarity of the cells, which means they help in the establishment of the anterior-posterior polarity or dorsal ventral polarity of cells.
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Which statement about Hox genes is false?
a.
They are expressed in similar patterns in the embryos of both mice and flies.
b.
They include a conserved region of base pairs called the homeobox.
c.
They are arranged in similar clusters of genes in both mice and flies.
d.
They are part of the so-called genetic toolkit.
e.
Because of their important functional roles, they evolved rapidly in both mammals and flies.
Absence of bicoid mRNA from a Drosophila egg leads to theabsence of anterior larval body parts and mirror-imageduplication of posterior parts. This is evidence that the productof the bicoid gene(A) normally leads to formation of head structures.(B) normally leads to formation of tail structures.(C) is transcribed in the early embryo.(D) is a protein present in all head structures.
Developmental genes are often highly conserved. However, organisms with very similar genes can appear quite different. How is this possible?
A. The genes may usually undergo mutation during development, resulting in the production of varied proteins in individual cells.
B. If an identical gene is turned on at different stages in development, it can have very different effects.
C. Even if genes are quite similar, they always produce proteins with different functions.
D. If the genes are very similar, they must always be expressed similarly (at similar times in development) but may sometimes still have varying effects.
Chapter 18 Solutions
Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)
Ch. 18.1 - Prob. 1CCCh. 18.2 - Prob. 1CCCh. 18.2 - Explain the advantage of the systems biology...Ch. 18.2 - Prob. 3CCCh. 18.3 - The best estimate is that the human genome...Ch. 18.3 - Prob. 2CCCh. 18.3 - Prob. 3CCCh. 18.4 - Discuss the characteristics of mammalian genomes...Ch. 18.4 - Which of the three mechanisms described in Figures...Ch. 18.4 - Prob. 3CC
Ch. 18.5 - Describe three examples of errors in cellular...Ch. 18.5 - Prob. 2CCCh. 18.5 - Prob. 3CCCh. 18.6 - Would you expect the genome of the macaque (a...Ch. 18.6 - Prob. 2CCCh. 18 - Prob. 1TYUCh. 18 - Prob. 2TYUCh. 18 - Two eukaryotic proteins have one domain in common...Ch. 18 - SCIENTIFIC INQUIRY The scientists mapping human...Ch. 18 - FOCUS ON EVOLUTION Genes important in the...Ch. 18 - FOCUS ON INFORMATION The continuity of life is...Ch. 18 - SYNTHESIZE YOUR KNOWLEDGE Insects have three...
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- Homeobox genes (a) are found in fruit flies but no other animals (b) tend to be expressed in the order that they appear on a chromosome (c) contain a characteristic DNA sequence (d) b and c (e) a, b, and carrow_forwardWhen in fruit fly development does axes development begin? A. in the unfertilized egg stage when maternal effect genes deposit mRNA and proteins in specific locations B. in the early embryo stage when induction signals between neighboring cells identify where the cells are in three-dimensional space C. in the larval stage when body segments appear, and pattern formation is evident D. in the pupal stage when a gradient of morphogens is establishedarrow_forwardDiscuss the role of homeotic genes in development. Explain what happens to the phenotype of a fruit fly when a gain-of-function mutation in a homeotic gene causes the protein to be expressed in an abnormal region of the embryo. What are the consequences of a loss-of-function mutation in such a gene?arrow_forward
- The MyoD gene in mammals plays a role in skeletal muscle-cell differentiation, whereas the Hox genes are homeotic genes that play a role in the differentiation of particular regions of the body. Explain how the functions of these genes are similar and different.arrow_forwardWhy is it easier to manipulate embryonic stem cells to differentiate into various tissues than it is to manipulate a typical adult cell? a. As cells develop, signaling pathways can cause some genes to be turned off during development. b. Adult cells have different DNA content than do embryonic stem cells. c. Emybronic stem cells pose less of a threat for organ rejection as do an individual s own adult cells. d. It is no easier to manipulate emybronic stem cells to differentiate into various tissues than it is to manipulate a typical adult cell.arrow_forwardIf a mutation in a homeotic gene produced the following phenotypes, would you expect it to be a loss-of-function or a gain-offunction mutation? Explain your answer. A. An abdominal segment has antennae attached to it. B. The most anterior abdominal segment resembles the most posterior thoracic segment. C. The most anterior thoracic segment resembles the most posterior abdominal segment.arrow_forward
- Which of the following statements about the differential expression of human genes is correct? A. Differential expression does not occur during embryogenesis (development of the embryo). B. The unused genes in differentiated cells no longer retain the potential to be expressed. C. Gene expression patterns of all cells are identical. D. Every cell nucleus contains the complete genome established in the fertilized egg.arrow_forwardMaster regulatory genes play critical roles in development. Predict the MOST likely fate of a fly embryo where master regulatory genes were nonfunctional due to mutation. A. Cell division would stop, and the embryo would halt development. B. The embryo would be a collection of undifferentiated cells because they never get the message that will send them down a determination pathway. C. The embryo would be a combination of differentiated and undifferentiated cells because, even in the absence of a functional master regulatory gene, some cells will differentiate on their own. D. The embryo would continue to develop, but there is a high probability that some limbs may end up in the wrong place in the adult.arrow_forwardGive typing answer with explanation and conclusion What characteristics of the DSX protein enable the female- and male-specific isoforms of DSX to regulate the same genes but with different outcomes in female and male development? [multiple answers possible] A.The two isoforms are different alleles of the same gene B.The two isoforms have different DNA-binding domains C.The two isoforms are lncRNAs involved in dosage compensation D.The two isoforms differ in their activation domain E.The two isoforms share the same activation domain F. The two isoforms share the same DNA-binding domainarrow_forward
- Which of the following statements is incorrect? a. Some gene expression patterns can be passed to an individual's offspring. b. Expression of a master regulator triggers a gene expression cascade. c. X chromosome inactivation is necessary for normal development of male mammals.arrow_forwardWhat piece of a transcript is utilized to localize the mRNA and why is this critical to development? a. 3'UTR; protein gradients have a large influence on gene expression of cells b. 5'UTR; protein gradients have a large influence on gene expression in cells c. the promoter; it has a large influence on protein production within a cell d. The TATA box; it has a large influence on protein production within a cellarrow_forwardGive examples of genes that affect development in fruit flies by regulating gene expression at the level of (a) transcription and (b) translation.arrow_forward
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