The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified. Concept introduction: The acetoacetic ester is a β -dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide . In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Question

Want to see the full answer?

Answer 1

Question

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Write the products of the following acid-base reactions: (a) CH3OH + H2SO4 ² ? (b) CH3OH + NANH2 2 ? (c) CH3NH3+ Cl- + NaOH ?

Which of the following molecules form a carboxylic acid upon oxidation? (A) (C) OH хи (B) (D) ОН LOH

What is the product formed when pentyne reacts with disiamylborane? (A) Pentanol (B) Pentanone (C) Pentanal (D) Pentan-2-ol

Answer 2

Question

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Answer 6

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Answer 7

Chapter 18, Problem 4Q

Interpretation Introduction

Interpretation:

The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.

Concept introduction:

The acetoacetic ester is a β-dicarbonyl compound, easily converted into enolatethat further reacts with an alkyl halide.

In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 11

Ch. 18 - Prob. 1PP Ch. 18 - Practice Problem 18.2 Would optically active...Ch. 18 - Prob. 3PP Ch. 18 - Practice Problem 18.4 Why do we say that the...Ch. 18 - Prob. 5PP Ch. 18 - Practice Problem 18.6 (a) Write a reaction...Ch. 18 - PRACTICE PROBLEM 18.7 Show how you would use the...Ch. 18 - Practice Problem 18.8 The acetoacetic ester...Ch. 18 - Practice Problem 18.9 In the synthesis of the keto...Ch. 18 - PRACTICE PROBLEM 18.10 How would you use the...

Solution Summary: The author explains the preferred base for alkylation of monoalkylacetoacetic ester.

Concept explainers

Want to see the full answer?

Chapter 18 Solutions