Glycine dissolved in pure water whether will have a protonated C O O H group and an unprotonated N H 2 group has to be determined. Concept Introduction: Dissociation constant of acid: An acid dissociation constant ( K a ) is a quantitative measure of the strength of an acid in solution. Dissociation constant of base: A base dissociation constant ( K b ) is a quantitative measure of the strength of a base in solution. Zwitterion: This term is used mostly in case of amino acids. Zwitterion is a molecule with two or more functional groups, of which at least one has a positive and one has a negative electrical charge and the net charge of the entire molecule is zero.
Glycine dissolved in pure water whether will have a protonated C O O H group and an unprotonated N H 2 group has to be determined. Concept Introduction: Dissociation constant of acid: An acid dissociation constant ( K a ) is a quantitative measure of the strength of an acid in solution. Dissociation constant of base: A base dissociation constant ( K b ) is a quantitative measure of the strength of a base in solution. Zwitterion: This term is used mostly in case of amino acids. Zwitterion is a molecule with two or more functional groups, of which at least one has a positive and one has a negative electrical charge and the net charge of the entire molecule is zero.
Glycine dissolved in pure water whether will have a protonated COOH group and an unprotonated NH2 group has to be determined.
Concept Introduction:
Dissociation constant of acid:
An acid dissociation constant (Ka) is a quantitative measure of the strength of an acid in solution.
Dissociation constant of base:
A base dissociation constant (Kb) is a quantitative measure of the strength of a base in solution.
Zwitterion:
This term is used mostly in case of amino acids. Zwitterion is a molecule with two or more functional groups, of which at least one has a positive and one has a negative electrical charge and the net charge of the entire molecule is zero.
(b)
Interpretation Introduction
Interpretation:
[+NH3CH2COO−]/[+NH3CH2COOH] ratio has to be determined at pH 5.5.
Concept Introduction:
Henderson-Hasselbalch Equation:
The Henderson-Hasselbalch Equation can be written for any conjugate acid–base pair as given bellow,
pH=pKa+log([Base][Acid])
Where,
pH=-log[H3O+]pKa=-logKaKa=Dissociation constantofacid[Base]=Concentration of base[Acid]=Concentration of acid
(c)
Interpretation Introduction
Interpretation:
Structure of lysine at pH1, physiological pH(∼7) and pH13 has to be determined.
Concept Introduction:
Acidic pH means H+ ions are available. In other words, the concentration of H+ ion is more. So the base present in the system will be protonated.
Basic pH means the concentration of H+ ion is less, the concentration of OH− ion is more. So the acid present in the system will be deprotonated.
Physiological pH(∼7) means neutral. The concentration of H+ ion and OH− ion are same. At such condition zwitterion will be formed.
Zwitterion:
This word is used mostly in case of amino acids. Zwitterion is a molecule with two or more functional groups, of which at least one has a positive and one has a negative electrical charge and the net charge of the entire molecule is zero.
(d)
Interpretation Introduction
Interpretation:
The structure of glutamic acid at pH 1, physiological pH(∼7) and pH13 has to be identified from the given options.
Concept Introduction:
Acidic pH means H+ ions are available. In other words, the concentration of H+ ion is more. So the base present in the system will be protonated.
Basic pH means the concentration of H+ ion is less, the concentration of OH− ion is more. So the acid present in the system will be deprotonated.
Physiological pH(∼7) means neutral. The concentration of H+ ion and OH− ion are same. At such condition zwitterion will be formed.
Zwitterion:
This term is used mostly in case of amino acids. Zwitterion is a molecule with two or more functional groups, of which at least one has a positive and one has a negative electrical charge and the net charge of the entire molecule is zero.