EBK HUMAN PHYSIOLOGY
8th Edition
ISBN: 9780134704227
Author: Silverthorn
Publisher: YUZU
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Chapter 19, Problem 22RQ
a.
Summary Introduction
To determine: The response of rodent nephron towards inulin.
Introduction: Excretion is the process of eliminating or expelling the waste material from the living cells. The waste matter in living organisms is carbon dioxide, water, urea, uric acid, ammonia, and many more.
b.
Summary Introduction
To sketch: The line on the given graph that represents the net reabsorption or secretion.
Introduction: The nephrons present in the kidneys are designed to maintain body fluid homeostasis. Homeostasis is the process of keeping body fluid volumes stable as well as maintaining the level of salts and minerals.
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Na+ ions are actively transported out of the tubules to help set up the countercurrent multiplier. Which of the following are sites of active Na+ ion transport in the nephron?
The renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations.
For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion
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Draw a schematic diagram showing the flow of water and salts in the proximal tubule of the kidney. In this diagram, put the lumen on the left side of the diagram and the extracellular fluids on the right side of the diagram. Indicate where the lumen is, where the extracellular fluid is, where the apical portion of the cell is, and show the location of the proteins that are responsible for the movement of water and salts and glucose reabsorption in this area of the kidney
Chapter 19 Solutions
EBK HUMAN PHYSIOLOGY
Ch. 19.1 - Ion regulation is a key feature of kidney...Ch. 19.1 - What happens to the force of cardiac contraction...Ch. 19.2 - If net filtration out of glomerular capillaries...Ch. 19.2 - If net reabsorption into peritubular capillaries...Ch. 19.3 - Name one way in which filtration and secretion are...Ch. 19.3 - A water molecule enters the renal corpuscle from...Ch. 19.3 - Prob. 7CCCh. 19.4 - Why is the osmotic pressure of plasma in efferent...Ch. 19.4 - If a hypertensive persons blood pressure is...Ch. 19.4 - If systemic blood pressure remains constant but...
Ch. 19.4 - A person with cirrhosis of the liver has...Ch. 19.7 - If plasma creatinine = 1.8 mg/100 mL plasma, urine...Ch. 19 - List and explain the significance of the five...Ch. 19 - List and explain the six major kidney functions.Ch. 19 - At any given time, what percentage of cardiac...Ch. 19 - Prob. 4RQCh. 19 - Arrange the following structures in the order that...Ch. 19 - Name the three filtration barriers that solutes...Ch. 19 - Prob. 7RQCh. 19 - What does the abbreviation GFR stand for? What is...Ch. 19 - Identify the following structures, then explain...Ch. 19 - In which segment of the nephron does most...Ch. 19 - Match each of the following substances with its...Ch. 19 - Prob. 12RQCh. 19 - Prob. 13RQCh. 19 - Prob. 14RQCh. 19 - Map the following terms. You may add terms if you...Ch. 19 - Define, compare, and contrast the items in the...Ch. 19 - What are the advantages of a kidney that filters a...Ch. 19 - Prob. 18RQCh. 19 - Diagram the micturition reflex. How is this reflex...Ch. 19 - Antimuscarinic drugs are the accepted treatment...Ch. 19 - Draw a section of renal tubule epithelium showing...Ch. 19 - Prob. 22RQCh. 19 - Read the box on hemodialysis on p. 603 and see if...Ch. 19 - Graphing question: You are given a chemical Z and...Ch. 19 - Prob. 25RQCh. 19 - Prob. 26RQCh. 19 - Dwight was competing for a spot on the Olympic...Ch. 19 - You are a physiologist taking part in an...Ch. 19 - If 140 liters of plasma are filtered in a day, and...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the unique features of Henle loops that contribute to countercurrent multiplication during urine production? Provide an explanation of how countercurrent multiplication is facilitated in nephrons, including all the factors that contribute to it.arrow_forwardOne type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle. A) What does it mean to inhibit the transport of sodium ions in the loop of Henle? B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.arrow_forwardWhat would be the effect of a dysfunctional Na+/K+ pump in the cells of the following parts of the nephro:a. Proximal convoluted tubule?b. Loop of Henle?c. Distal convoluted tubule?arrow_forward
- Atrial Natriuretic Peptide helps to reduce overall blood pressure in a variety of ways. One way is by increasing Glomerular Filtration Rate. a. Why/how would increasing GFR cause decreased blood pressure? b. To increase GFR, would Atrial Natriuretic Peptide cause constriction or dilation of afferent arterioles at the kidneys? The efferent arterioles?arrow_forwardA 28-year-old man has a fasting serum glucose concentration of 140 mg/dL and a glomerular filtration rate of 125 ml/min. The renal transport maximum for glucose in this patient is 300 mg/min. Which of the following best represents the rate of urinary glucose excretion (in mg/min) in this man? (A) 0 (B) 100 (C) 200 (D) 300 (E) 400arrow_forwardBased on the graph on the right,which describes the clearance rate through the basement membrane of the glomerulus, which protein would generate the most oncotic pressure at equivalentconcentration?(a) albumin (66 kDa, 3.5 nmradius)(b) myoglobin (17 kDa, 2.23 nm radius)(c)γ-globulin (150 kDa, 4.54 nm radius) (b)Justify your answer.arrow_forward
- The process of hydrogen ion secretion in the proximal convoluted tubule occurs via which of the following mechanisms? Choose from the following: (A) hydrogen ions diffuse out of the glomerular filtrate of the proximal convoluted tubule, through extracellular fluid and into the peritubular blood (B) carbon dioxide diffuses into the proximal convoluted tubule cell from peritubular capillary blood; undergoes a chemical reaction to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ion diffuses into the glomerular filtrate of the proximal convoluted tubule (C) hydrogen ions diffuse out of the peritubular capillary blood, through extracellular fluid and into the filtrate of the proximal convoluted tubule (D) carbon dioxide diffuses into the proximal convoluted tubule cell from the glomerular filtrate; undergoes a chemical reacdtion to form carbonic acid; dissociates into hydrogen and bicarbonate ions; the hydrogen ions diffuse into the peritubular bloodarrow_forwardFred was diagnosed 6 months ago with liver cancer. His liver is no longer able to make the necessary amount of proteins needed by the body. What effect, if any, would this have on the net glomerular filtration rate? (Hint, decide which of the 3 forces contributing to the net filtration rate is affected. Then adjust numbers in the equation to determine if there is an increase, decrease, or no change to the net filtration rate). Group of answer choices A) Blood colloid osmotic pressure would be decreased, increasing the net glomerular filtration rate. B) Blood colloid osmotic pressure would be decreased, decreasing the net glomerular filtration rate. C) Capsular hydrostatic pressure would be decreased, increasing the net glomerular filtration rate. D) Capsular hydrostatic pressure would be decreased, decreasing the net glomerular filtration rate. E) There would be no effect on the net glomerular filtration rate.arrow_forwardWhat is the difference between filtration and reabsorption? Explain how hydrostatic, osmotic (or colloid oncotic), and osmosis influence fluid transport across the nephron.arrow_forward
- What evolutionary purpose does hyperosmotic urine serve? What would be the ramifications of being able to produce only isosmotic urine? How are countercurrent mechanisms able to accomplish this?arrow_forwardThe diagram below of part of a nephron shows some of the pressure gradients that are involved in the movement of fluids from blood to the glomerular filtrate within the Bowman's capsule. The numbers represent hydrostatic pressure in kPA. Afferent arteriole (9.32) Glomerulus Efferent arteriole (2.34) -Bowman's caps Colloid osmotic pressure of the plasma in the glomerular capillaries (4.26) Net fitration Distal convoluted Proximal convoluted tubule tubule (1.33)arrow_forwardMost of the glucose that crosses the filtration barrier is absorbed in which of the following lettered regions on the light micrographs of the kidney ?arrow_forward
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