Dwight was competing for a spot on the Olympic equestrian team. As his horse, Nitro, cleared a jump, the footing gave way, causing the horse to somersault, landing on Dwight and crushing him. The doctors feared kidney damage and ran several tests. Dwight’s plasma creatinine level was 2 mg/100 mL. His 24-hour urine specimen had a volume of 1 L and a creatinine concentration of 20 mg/mL. A second specimen taken over the next 24 hours had the same plasma creatinine value and urine volume, but a urine creatinine concentration of 4 mg/ mL. How many milligrams of creatinine are in each specimen? What is Dwight’s creatinine clearance in each test? What is his GFR? Evaluate these results and comment on Dwight’s kidney function.
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