EBK BIOLOGY
11th Edition
ISBN: 8220102797352
Author: Raven
Publisher: YUZU
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 19, Problem 6A
What would be the likely result of a mutation of the bcl-2 gene on the level of apoptosis
a. No change
b. A decrease in apoptosis
c. An increase in apoptosis
d. An initial decrease, followed by an increase in apoptosis
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Predict the effects of the following mutations on the ability of a cell to undergo apoptosis:a. Mutation in Bad such that it cannot be phosphorylated by protein kinase B (PKB)b. Overexpression of Bcl-2c. Mutation in Bax such that it cannot form homodimersOne common characteristic of cancer cells is a loss of function in the apoptotic pathway. Which of the mutations listed above might you expect to find in some cancer cells?
What would be the effect on the following processes in a cancer cells treated with Drug X. Match the process with the
likely effect of the drug.
Protein Translation
Apoptosis
Cell Proliferation
Production of new blood vessels
A. Inhibited
B. Activated
Tumors involve a malfunction in this cellular process. a. transcription b. translation c. phagocytosis d. mitosis
Chapter 19 Solutions
EBK BIOLOGY
Ch. 19 - During development, cells become a. differentiated...Ch. 19 - Prob. 2UCh. 19 - Prob. 3UCh. 19 - Prob. 4UCh. 19 - Plant meristems a. are only present during...Ch. 19 - Prob. 6UCh. 19 - The process of nuclear reprogramming a. is a...Ch. 19 - What is the common theme in cell determination by...Ch. 19 - The process of reproductive cloning a. shows that...Ch. 19 - Prob. 3A
Ch. 19 - Prob. 4ACh. 19 - The genes that encode the morphogen gradients in...Ch. 19 - What would be the likely result of a mutation of...Ch. 19 - MADS-box, and Hox genes are a. found only in...Ch. 19 - The fate map for C. elegans (refer to figure 19.3)...Ch. 19 - Prob. 2SCh. 19 - You have generated a set of mutant embryonic mouse...Ch. 19 - Assume you have the factors in hand necessary to...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- During apoptosis, rates of protein degradation ______ caused by _____ protease activity. Select one: a. increase, increase b. increase, decrease c. decrease, decrease d. decrease, increasearrow_forwardTwo mechanisms inducing Apoptosis, Extrinsic pathway and Intrinsic pathway, have difference and similarity. a What is the key protein that both pathway uses? b How can intrinsic pathway be initiated and what molecule is critical for that?arrow_forwardCancer cells can secrete factors which promote the formation of new blood vessels. The formation of the new blood vessels in this manner is called Select one: O a. carcinogenesis O b. angiogenesis O c. metastasis O d. apoptosis O e. contact inhibitionarrow_forward
- A drug that inhibits the kinase activity of AKT would MOST likely have which of the following effects? A. Increased GSK-3b activity and increased CyclinD synthesis B. Increased GSK-3b activity and decreased CyclinD synthesis C. Decreased GSK-3b activity and increased CyclinD synthesis D. Decrease GSK-3b activity and decreased CyclinD synthesisarrow_forwardMalignant tumor cells are characterized by all of the following properties except: A. loss of density-dependent (contact) inhibition B. reliance on aerobic respiration C. reduced dependence on aerobic respiration D. loss of anchorage dependence E. gain of unlimited proliferative potentialarrow_forwardCancer cells are distinguished from other normal cells by (select all that apply!): a. having abnormal nuclei. b. inducing angiogenesis. ☐ c. dividing uncontrollably. d. having mutations in their tumor-suppressor genes.arrow_forward
- Which of the following are charcteristics you would expect of a circulating tumor cell that has undergone Epithelial-Mesenchymal Transition (select all that apply)? A. Increased N-cahedrin expression B. Increased resistance to apoptosis C. Loss of ability to secrete fibronectin D. High cytokeratin expression E. Elevated PDGF Receptor Expressionarrow_forwardThe body produces a normal amount of testosterone. However, a particular cell you are studying has an unusually low number of testosterone receptors. How might the cell's response to testosterone be affected by its low number of testosterone receptors? A. The cell will activate more protein kinases in response to testosterone exposure than a cell with a normal number of testosterone receptors. B. The cell will make less mRNA in response to testosterone exposure. C. The cell will make less cAMP in response to testosterone exposure. D. The cell’s response to testosterone exposure will be identical to the response of a cell with a normal number of testosterone receptors.arrow_forwardA tumor suppressor gene regulates the cell cycle; an example is . Select one: a. positively, p21 b. negatively, cyclin c. positively, retinoblastoma d. negatively, retinoblastoma e. positively, RAS Cycle HW due Jump to. 4) Next pa cancer stem cellsarrow_forward
- Cancer cells may be more susceptible than normal cells to mitotic catastrophe in response to chemotherapeutic drugs because of which of the following (select all that apply)? A. They express unique receptors for those drugs on their surface B. They may be resistant to apoptosis C. Cancer cells have more efficient DNA repair mechanism than normal cells. D. Only cancer cells are actively dividing E. They may lack key G2/M checkpoint controlsarrow_forwardMost forms of cancer involvea. the activation of a single oncogene.b. the inactivation of a single tumor-suppressor gene.c. the activation of multiple oncogenes.d. the activation of multiple oncogenes and the inactivation ofmultiple tumor-suppressor genes.arrow_forwardDescribe in detail the relevance of apoptosis to cancer therapyarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY