Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 20, Problem 10PDQ
You observe that a particular gene is being transcribed during development. How can you tell whether the expression of this gene is under transcriptional or translational control?
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You observe that a particular gene is being transcribed during development. How can you tell whether the expression of this gene is under transcriptional or translational control?
A mutation occurs in a gene, resulting in it being expressed at the wrong time during development. Where is the mutation most likely to be found?
a) In the transcription start site (TSS)
b) In a TF binding site in the cis-regulatory region
c) In the coding sequence
d) In the 5' UTR
Describe two different types of pre-transcriptional control of gene expression? Give an example of each type.
Chapter 20 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 20 -
CASE STUDY |One foot or another
In humans the...Ch. 20 - CASE STUDY| One foot or another In humans the HOXD...Ch. 20 - CASE STUDY| One foot or another In humans the HOXD...Ch. 20 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 20 - Review the Chapter Concepts list on page 403. Most...Ch. 20 -
3. Nuclei from almost any source may be injected...Ch. 20 -
4. Distinguish between the syncytial blastoderm...Ch. 20 - (a) What are maternal-effect genes? (b) When are...Ch. 20 - (a) What are zygotic genes, and when are their...Ch. 20 - List the main classes of zygotic genes. What is...
Ch. 20 -
8. Experiments have shown that any nuclei placed...Ch. 20 - How can you determine whether a particular gene is...Ch. 20 -
10. You observe that a particular gene is being...Ch. 20 - What are Hox genes? What properties do they have...Ch. 20 -
12. The homeotic mutation Antennapedia causes...Ch. 20 - The Drosophila homeotic mutation spineless...Ch. 20 - A number of genes that control expression of Hox...Ch. 20 - In Arabidopsis, flower development is controlled...Ch. 20 - Prob. 16PDQCh. 20 - Dominguez et al. (2004) suggest that by studying...
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- At the molecular level, how do you think a gain-of-function mutation in a developmental gene might cause it to be expressed in the wrong place or at the wrong time? Explain what type of DNA sequence would be altered.arrow_forwardWhich of the following gene expression regulatory mechanisms saves the most energy but takes the longest to fully express the genes once signaled? a. transcriptional regulation b. post-transcriptional regulation c. post-translational regulation d. translational regulationarrow_forwardGive examples of genes that affect development in fruit flies by regulating gene expression at the level of (a) transcription and (b) translation.arrow_forward
- How can three transcription regulators during development create eight different cell types?arrow_forwardWhat is the role of histone proteins in controlling gene expression?arrow_forwardMany genes important in development are regulated by effecting their mRNA. What is the mechanism responsible for this regulation? DNA methylation phosphorylation of amino acids histone modifications RNA interferencearrow_forward
- How is it that only a few transcription factors can initiate cell type specific gene expression?arrow_forwardWhich of the following is an example of post-transcriptionalcontrol of gene expression?(A) the addition of methyl groups to cytosine bases of DNA(B) the binding of transcription factors to a promoter(C) the removal of introns and alternative splicing of exons(D) gene amplification contributing to cancerarrow_forwardImagine you are a cell and you need to activate ("turn on") a gene as quickly as possible. What type of gene expression regulation would you use to achieve this?arrow_forward
- What determines which transcription factors will be able to regulate a particular gene's expression? A. The collection of control element sequences that are associated with that gene B. The location of that gene sequence (which chromosome it is located on) C. The sequence of introns present in that gene D. The sequence of exons present in that gene ..arrow_forwardWhat is effect of turning on and off of genes? How do we measure gene expression? What is gene regulation, explain extensively?arrow_forwardIn the gene in the fruit fly (Drosophila) called antennepedia. It controls the formation of which structures? What happens when it is mutated?arrow_forward
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