Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 20, Problem 16PDQ
Summary Introduction

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The control of expression of homeotic genes present in Arabidopsis and Drosophila, by Polycomb genes, which are evolutionary divergent sets of the genes.

Introduction:

Homeotic genes are the genes that are responsible for the determination of the fate of each cell type for the formation of a specific structure or organ in an adult body. They are the part of the zygotic genes and are expressed at the embryonic stage of the organism’s development. Different sets of these genes control the development and organization of the body plan in both plants and animals, respectively.

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In Drosophila, both fushi tarazu (ftz) and engrailed (eng) genes encode homeobox transcription factors and are capable of eliciting the expression of other genes. Both genes work at about the same time during development and in the same region to specify cell fate in body segments. To discover if ftz regulates the expression of engrailed;if engrailed regulates ftz; or if both are regulated by another gene, you perform a mutant analysis. In ftz embryos (ftz/ ftz) engrailed protein is absent; in engrailed embryos (eng/eng) ftz expression is normal. What does this tell you about the regulation of these two genes—does the engrailed gene regulate ftz, or does the ftz gene regulate engrailed?
In times of nutrient stress, the cellular slime mold Dictyostelium discoideum develops one of two cell types: pre-stalk and pre-spore. Scientists studying this development discovered that the pH of individual cells regulates the type of cell that is formed. Which of the following claims could scientists make about how environmental cues affect the gene expression of Dictyostelium discoideum? A - A response to nutrient deprivation leads to a change in pH that causes mutation in the cells, forming the different cell types. B - A response to nutrient deprivation leads to a change in pH that disrupts the cells, forcing them to develop into certain cell types. C - A response to environmental stress leads to a change in pH that triggers transcription factors to differentiate the cell type that will be formed. D - A response to environmental stress leads to a change in pH and a decrease in transcription factors that differentiate the cell type that will be formed.
Would the pattern of segment-polarity gene expression be normal if one or more gap genes were not expressed properly? Why or why not?
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