Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 20, Problem 16PDQ
Summary Introduction
To review:
The control of expression of homeotic genes present in Arabidopsis and Drosophila, by Polycomb genes, which are evolutionary divergent sets of the genes.
Introduction:
Homeotic genes are the genes that are responsible for the determination of the fate of each cell type for the formation of a specific structure or organ in an adult body. They are the part of the zygotic genes and are expressed at the embryonic stage of the organism’s development. Different sets of these genes control the development and organization of the body plan in both plants and animals, respectively.
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In Drosophila, both fushi tarazu (ftz) and engrailed (eng) genes encode homeobox transcription factors and are capable of eliciting the expression of other genes. Both genes work at about the same time during development and in the same region to specify cell fate in body segments. To discover if ftz regulates the expression of engrailed;if engrailed regulates ftz; or if both are regulated by another gene, you perform a mutant analysis. In ftz embryos (ftz/ ftz) engrailed protein is absent; in engrailed embryos (eng/eng) ftz expression is normal. What does this tell you about the regulation of these two genes—does the engrailed gene regulate ftz, or does the ftz gene regulate engrailed?
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Chapter 20 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 20 -
CASE STUDY |One foot or another
In humans the...Ch. 20 - CASE STUDY| One foot or another In humans the HOXD...Ch. 20 - CASE STUDY| One foot or another In humans the HOXD...Ch. 20 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 20 - Review the Chapter Concepts list on page 403. Most...Ch. 20 -
3. Nuclei from almost any source may be injected...Ch. 20 -
4. Distinguish between the syncytial blastoderm...Ch. 20 - (a) What are maternal-effect genes? (b) When are...Ch. 20 - (a) What are zygotic genes, and when are their...Ch. 20 - List the main classes of zygotic genes. What is...
Ch. 20 -
8. Experiments have shown that any nuclei placed...Ch. 20 - How can you determine whether a particular gene is...Ch. 20 -
10. You observe that a particular gene is being...Ch. 20 - What are Hox genes? What properties do they have...Ch. 20 -
12. The homeotic mutation Antennapedia causes...Ch. 20 - The Drosophila homeotic mutation spineless...Ch. 20 - A number of genes that control expression of Hox...Ch. 20 - In Arabidopsis, flower development is controlled...Ch. 20 - Prob. 16PDQCh. 20 - Dominguez et al. (2004) suggest that by studying...
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- A strain of Arabidopsis thaliana possesses a mutation in the APETALA2 gene. As a result of this mutation, much of the 3′ UTR of the mRNA transcribed from the gene is deleted. What is the most likely effect of this mutation on the expression of the APETALA2 gene?arrow_forwardWhat kind of response is seen via temperature stress in Drosophila? Are these kinds of elements conserved in all organisms? What is the role of the final protein element translated?arrow_forwardIn a particular organism, there are two similar genes called YFG1 and YFG2. YFG1 is expressed in the liver and not in the pancreas, and YFG2 is expressed in the pancreas but not the liver. Neither YFG1 nor YFG2 is expressed in the heart. If you extract DNA from heart cells, do you expect to see the YFG2 gene? Explain why. Do you expect to see the YFG1 protein when you analyze protein extract from liver cells? And from pancreas cells? And from heart cells? Explain why. Is it possible to produce YFG1 and YFG2 proteins via alternative splicing? Explain one possible way (mechanism) to regulate the expression of YFG1 gene.arrow_forward
- How do we know that the mutant Bar-eye phenotype in Drosophila is due to a duplicated gene region rather than to a change in the nucleotide sequence of a gene?arrow_forwardThe figure below shows the distribution of proteins during embryo development in Drosophila. These proteins are encoded by which types of genes? Which proteins regulate the expression of these genes?arrow_forwardWhat is the signaling pathway that mediates the organizing activity of the A/P organizer in the Drosophila wing disc? Describe two experiments that suggest this pathway functions to organize pattern and promote growth along the anterior/posterior axis of wing imaginal discs.arrow_forward
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- As shown in Figure 13-22, how many different transcription factors govern where the Distal-less (Dll) gene willbe expressed?arrow_forwardExplain why loss-of-function hedgehog and smoothened mutations yield the same phenotype in flies, but a loss-of- function patched mutation yields the opposite phenotype.arrow_forwardProtein levels and mRNA levels for a particualr gene don’t always match. For example, the GCN4 gene in yeast is always producing mRNA, but the Gcn4 protein is only made when the cells are starved. What does this mean for diagnostic techniques that try to look at gene expression?arrow_forward
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