Chapter 21, Problem 16.2P

a.

Summary Introduction

To determine: The probability that the given couple produce a child with the genetic disorder.

Introduction: Genetic disorders are caused due to abnormalities that occur in one or more genes. These abnormalities can be due to changes in number or structure of the chromosome.

b.

Summary Introduction

To determine: The probability that the given couple produce a child is a carrier of the genetic disorder.

Introduction: Autosomal dominant disorders can occur both in homozygous and heterozygous conditions while autosomal recessive disorder can occur only in homozygous condition. A carrier consists of a defective allele responsible for an autosomal recessive disorder.

c.

Summary Introduction

To determine: The probability that the given couple produce a child who is phenotypically normal.

Introduction: A homozygote has both identical alleles in the genotype while the alleles present in a heterozygote are non-identical. It has one dominant and one recessive allele.

d.

Summary Introduction

To determine: The probability that the given couple produce a child who is not a carrier.

Introduction: A carrier can be symptomatic or asymptomatic. If the carrier is symptomatic, he/she is not affected but has few symptoms of the disease. If the carrier is asymptomatic, he/she is phenotypically normal.