Chapter 21, Problem 1IQ

In what ways would third-generation sequencing be different from sequencing by synthesis?

Summary Introduction

To determine: The types of organisms that have been best studied using metagenomics.

Introduction: For sequencing the genome of humans, The Human Genome Project was introduced. For mapping any genome, the ultimate goal is to determine the whole chromosomes’ nucleotide sequence. The technological advances bring about many less-expensive technical approaches for foster sequencing.

Explanation of Solution

The technological advances facilitated an approach called metagenomics that enables the sequencing of a mixture of deoxyribonucleic acid (DNA) sequence of entire microbial population. In metagenomics process, the DNA sequences of microbial population are collected and sequenced from an environmental sample without the need for lab culture of each microbial species separately.