Concept explainers
(a)
Interpretation: The validation of the given statement concerning the type of inhibitor has to be stated.
Concept introduction: A chemical substance which reduces or stops the catalytic function of an enzyme by binding to it is known as an enzyme inhibitor. There are three modes of inhibition: Reversible competitive inhibition, Reversible non-competitive inhibition and irreversible inhibition.
(b)
Interpretation: The validation of the given statement concerning the type of inhibitor has to be stated.
Concept introduction: A chemical substance which reduces or stops the catalytic function of an enzyme by binding to it is known as an enzyme inhibitor. There are three modes of inhibition: Reversible competitive inhibition, Reversible non-competitive inhibition and irreversible inhibition.
(c)
Interpretation: The validation of the given statement concerning the type of inhibitor has to be stated.
Concept introduction: A chemical substance which reduces or stops the catalytic function of an enzyme by binding to it is known as an enzyme inhibitor. There are three modes of inhibition: Reversible competitive inhibition, Reversible non-competitive inhibition and irreversible inhibition.
(d)
Interpretation: The validation of the given statement concerning the type of inhibitor has to be stated.
Concept introduction: A chemical substance which reduces or stops the catalytic function of an enzyme by binding to it is known as an enzyme inhibitor. There are three modes of inhibition: Reversible competitive inhibition, Reversible non-competitive inhibition and irreversible inhibition.
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Chapter 21 Solutions
General, Organic, and Biological Chemistry
- Indicate whether each of the following statements describes a reversible competitive inhibitor, a reversible noncompetitive inhibitor, or an irreversible inhibitor. More than one answer may apply. a. It bonds covalently to the enzyme active site. b. The inhibitor effect can be reversed by the addition of more substrate. c. Inhibitor structure must be somewhat similar to that of the substrate. d. The inhibitor and substrate cannot bind to the enzyme simultaneously.arrow_forwardBased on the graphical information in Problem 21-41 about enzymes A and B indicate whether the enzyme activity of enzyme B increases or decreases when the following changes in reaction conditions are made. a. pH decreases from 7.6 to 7.2 b. pH increases from 7.2 to 7.4 c. temperature decreases from 37.8C to 37.6C d. temperature increases from 38.2C to 38.4Carrow_forwardIndicate whether each of the following statements concerning enzymes and their mode of action are true or false. a. According to the induced-fit model of enzyme action, a substrate must be changed into a cofactor before a chemical reaction occurs. b. The active site of an enzyme is the location within the enzyme where catalysis takes place. c. The protein portion of a conjugated enzyme can accommodate several substrates at the same time. d. Simple enzymes do not have active sites, whereas conjugated enzymes do have active sites.arrow_forward
- Describe the importance of zymogens in the body. Give an example of an enzyme that has a zymogen.arrow_forwardIndicate whether each of the following statements about an enzyme active site is true or false. a. It is the location where substrate molecules are produced. b. It always has a fixed, rigid geometry. c. It always has a geometrical shape exactly complementary to that of substrate. d. It always accommodates several structurally related substrates.arrow_forwardThe human body has an average pH of about 7 and a temperature of about 37C. Use graphs to illustrate enzyme activity in the human body as a function of the following: a. Substrate concentration b. Enzyme concentration c. pH include pH optimum value d. Temperature include temperature optimum valuearrow_forward
- Based on the graphical information in Problem 21-41 about enzymes A and B a. What is the optimum pH for enzyme B? b. What is the optimum temperature for enzyme A? c. Which enzyme has the greater activity at a pH of 7.2? d. Which enzyme has the greater activity at a temperature of 37.2C?arrow_forwardIndicate whether each of the following statements about an enzyme active site is true or false. a. It is the location where substrate molecules are converted to product molecules. b. It always has a shape that has a degree of flexibility to it. c. It always has a geometrical shape identical to that of substrate. d. It always accommodates only one specific substrate.arrow_forwardExplain how the pasteurization of milk utilizes one of the factors that influence enzyme activity.arrow_forward
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