Concept explainers
(a)
Interpretation:
The
Concept introduction:
The amino acid formed (R-group) from the acetamidomalonic (like N-phthalimidomalonic) ester synthesis is only depended upon the alkyl halide used in the reaction.
That means,
(b)
Interpretation:
The alkyl halide that used to synthesize of phenylalanine by acetamidomalonic ester synthesis has to be given.
Concept introduction:
The amino acid formed (R-group) from the acetamidomalonic (like N-phthalimidomalonic) ester synthesis is only depended upon the alkyl halide used in the reaction.
That means,
Want to see the full answer?
Check out a sample textbook solutionChapter 21 Solutions
Organic Chemistry (8th Global Edition) - Does NOT include MasteringChemistry
- How to use streckers synthesis to prepare phenylalanine in the laboratoryarrow_forwardWhy is anisole nitrated more rapidly than thioanisole under the same conditions?arrow_forwardTriethylenemelamine (TEM) is an antitumor agent. Its activity is due to its ability to cross-link DNA. a. Explain why it can be used only under slightly acidic conditions. b. Explain why it can cross-link DNA.arrow_forward
- Triethylenemelamine (TEM) is an antitumor agent. Its activity is due to its ability to cross-link DNA. a. Explain why it can be used only under slightly acidic conditions.b. Explain why it can cross-link DNA.arrow_forwardlactic acid was disscolved in an aqueous solution at a ph of 4.9 the pka of lactic acid dissociation is 3.9 what are the fractions of positiviely negatively and neutrally charged molecules of lactic acid in the solutionarrow_forwardSynthesis of p-Bromoaniline Why is the protection of the amine function needed in this reaction? a) The protection increases the selectivity for the ortho substitution. b) The protection increases the reactivity of the reactant in the bromination. c) The protection changes the regioselectivity of reaxtion.arrow_forward
- Explain why DMF(dimethyformamide) is a particularly good solvent for the synthesis of n-Hexyl acetate reaction?arrow_forwardHydrolysis of acetic anhydride is competing reaction to the amidization. Write a balanced equation for the hydrolysis reaction. With that reaction equation as a reference, how might be hydrolysis minimized?arrow_forwardCan N-Hydroxysuccinimide undergo acidic hydrolysis with acid like h2so4 to produce diester compound? Thanks.arrow_forward
- Draw the mechanism for the synthesis of disopyramide with curly head arrows showing the movement of electrons.arrow_forwardExplain about Stemoamide ?arrow_forwardWhat is the name of the macrolide shown? A. Erythromycin A B. Erythromycin B C. Erythromycin C D. Clarithromycin E. Azithromycin F. Dirithromycin Which of the following functional groups is absent in the structure? A. Ester B. Ketone C. Carboxylic acid D. Ether E. Aminoarrow_forward