What Is Life? A Guide to Biology with Physiology
4th Edition
ISBN: 9781319065447
Author: Jay Phelan
Publisher: W. H. Freeman
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Chapter 22, Problem 10MC
Summary Introduction
Introduction:
Humans get accustomed to the oxygen levels at higher altitudes due to the production of more diphosphoglyceric acid.
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Which of the following causes an increase in hemoglobin’s 02 affinity?
A. An increase in the partial pressure of oxygen.
B. A decrease in ph
C. An increase in the concentration of 2,3 -BPG
D. An increase in the partial pressure of carbon dioxide
Do the following conditions cause hemoglobin to release more O2 to the tissues or to absorb more O2?(a) Raising the temperature(b) Increased production of CO2(c) Increasing the H+ concentration
Which of the following statements is FALSE regarding a rightward shift in the hemoglobin-oxygen dissociation curve?
A) Affinity for oxygen is increased.
B) Oxygen loading onto the hemoglobin is increased.
C) Hemoglobin is more saturated at a given PO2.
D) It can be caused by a decrease in temperature.
E) It can be caused by a decrease in blood pH.
Chapter 22 Solutions
What Is Life? A Guide to Biology with Physiology
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- What is the biological advantage to the sigmoidal binding curve of hemoglobin for oxygen? A. It ensures that hemoglobin has a high affinity for oxygen. B. It allows hemoglobin to bind oxygen irreversibly. C. It ensures that hemoglobin can bind oxygen only weakly. D. It allows hemoglobin to shift between low and high affinities for oxygen.arrow_forwardWhich of the following statements is FALSE regarding a leftward shift in the hemoglobin-oxygen dissociation curve? A) Affinity for oxygen is increased. B) Oxygen loading onto the hemoglobin is increased. C) Hemoglobin is more saturated at a given PO2. D) It can be caused by a decrease in temperature. E) It can be caused by a decrease in blood pH.arrow_forwardWhich of the following concerning hemoglobin is true? a) BPG decreases at high altitudes and causes more O2 offloading in tissues b) As pH increases, [CO2] increases in tissues, causing more O2 release in tissue c) The R state is stabilized by CO2 binding, whereas the T state is stabilized by O2 binding d) About 38% of oxygen dissociates from hemoglobin in tissues e) Hemoglobin has a higher affinity for oxygen than carbon monoxide My guess is D.arrow_forward
- Which of the following concerning hemoglobin is true? a) BPG decreases at high altitudes and causes more O2 offloading in tissues b) As pH increases, [CO2] increases in tissues, causing more O2 release in tissue c) The R state is stabilized by CO2 binding, whereas the T state is stabilized by O2 binding d) About 38% of oxygen dissociates from hemoglobin in tissues e) Hemoglobin has a higher affinity for oxygen than carbon monoxide My guess is D. What following statement is TRUE concerning motifs and domains? a) Both motifs and domains are independently stable. b) Domains undergo dynamic individual changes that affect the entire protein c) B-a-ß loops, B barrels, and helix-turn-helix structure are types of domains d) Motifs and domains are part of secondary structural elements e) Ab initio computations predict motif folds accurately a majority of the time My guess is B. Which of the following is TRUE under the following conditions: an enzyme displaying Michaelis-Menten kinetics…arrow_forwardHow does an increased level of 2,3-BPG help our bodies compensate through crises of a low availability of external oxygen? Highlight the action of 2,3-BPG on hemoglobin in your answer.arrow_forwardWhich of the links below are true? a) The cysteine moieties in the beta globulin - nitric oxide transport b) The globe component in hemoglobin - carbon dioxide transport c) The home group in the hemoglobin - oxygen transport d) Carbonic anhydrase - carbon dioxide transportarrow_forward
- After a person hypoventilates (such as by holding their breath), what can be detected on a molecular level? A. Increase in carbon dioxide is detected by both central and peripheral chemoreceptors. B. Decrease in oxygen is detected by both ventral and peripheral chemoreceptors. C. Decrease in carbon dioxide is detected by both central and peripheral chemoreceptors.arrow_forwardWhich of the following is true about the proximal histidine of hemoglobin? A. It forms a hydrogen bond with bound oxygen. B. It is bonded to the Fe2+ atom coordinated by heme C. It binds oxygen D. It is not consumed in myoglobinarrow_forwardWith the Bohr effect, more oxygen is released because a(n)____. a) increase in pH(alkalosis) strengthens the hemoglobin-oxygen bond b) increase in pH(alkalosis) weakens the hemoglobin-oxygen bond c) decrease in pH (acidosis) weakens the hemoglobin-oxygen bond d) decrease in pH (acidosis) strengthens the hemoglobin-oxygen bondarrow_forward
- Which of the following factors would increase the amount of oxygen discharged by hemoglobin to peripheral tissues? a. decreased amounts of DPG b. increased tissue PO2 c. decreased pH d. decreased temperature e. all of the abovearrow_forwardThe information provided suggests that: A. hemoglobin has more affinity to oxygen than to carbon monoxide. B. hemoglobin has more affinity to carbon dioxide than to carbon monoxide. C .carbon monoxide likely shifts the O2-Hb dissociation curve to the right. D. None of the abovearrow_forwardWhich of these statements does NOT correctly describe hypercapnia? a. It is observed in pulmonary diseases. b. It may be caused by hypoventilation. c. It occurs when CO2 in the blood is ventilated to the atmosphere at a rate faster than it is being produced by the tissues. d. It refers to excess CO2 in the arterial blood.arrow_forward
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