Connect Access Card for Anatomy & Physiology
2nd Edition
ISBN: 9781259133008
Author: Michael McKinley, Valerie O'Loughlin, Theresa Bidle
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 22.4, Problem 16WDYL
Which type of MHC class molecules is found on all nucleated cells and is used to communicate with cytotoxic T-lymphocytes? Which classes are displayed on APCs, and which class is used specifically to communicate with (a) helper T-lymphocytes and (b) cytotoxic T-lymphocytes?
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What types of antigens are displayed by MHCclass I molecules? By MHC class II molecules?
Why are MHC proteins so highly variable?
In regard to antigen presentation, MHC class I molecules usually present peptides derived from _____, whereas MHC class II molecules usually present peptides derived from _____.
a. intracellular cytosolic sources; vesicular system
b. phagolysosome; proteasomes
c. MIIC; self proteins
d. CLIP; HLA-DM
e. endocytic vesicles; endoplasmic reticulum.
Chapter 22 Solutions
Connect Access Card for Anatomy & Physiology
Ch. 22.1 - Which pathogen must enter a cell to replicate?...Ch. 22.2 - Prob. 2WDYLCh. 22.2 - What is the definition of a cytokine? How are...Ch. 22.2 - Prob. 4WDYLCh. 22.3 - Prob. 5WDYLCh. 22.3 - Prob. 6WDYLCh. 22.3 - How do NK cells accomplish the task of eliminating...Ch. 22.3 - Prob. 8WDYLCh. 22.3 - Prob. 9WDYLCh. 22.3 - Prob. 10WDYL
Ch. 22.3 - Prob. 11WDYLCh. 22.3 - Prob. 12WDYLCh. 22.4 - Prob. 13WDYLCh. 22.4 - What distinguishes a hapten from an antigen?Ch. 22.4 - Prob. 15WDYLCh. 22.4 - Which type of MHC class molecules is found on all...Ch. 22.4 - Prob. 17WDYLCh. 22.5 - Prob. 18WDYLCh. 22.5 - Prob. 19WDYLCh. 22.5 - Prob. 20WDYLCh. 22.6 - Prob. 21WDYLCh. 22.6 - How do cytokines released by helper T-lymphocytes...Ch. 22.6 - Prob. 23WDYLCh. 22.6 - Prob. 24WDYLCh. 22.6 - Prob. 25WDYLCh. 22.7 - Prob. 26WDYLCh. 22.7 - Prob. 27WDYLCh. 22.7 - Prob. 28WDYLCh. 22.8 - Prob. 29WDYLCh. 22.8 - What are the six major functions of antibodies?...Ch. 22.8 - Which subclass of antibodies is most prevalent?...Ch. 22.9 - Prob. 32WDYLCh. 22.9 - Prob. 33WDYLCh. 22.9 - Prob. 34WDYLCh. 22 - _____ 1. All of the following are phagocytic cells...Ch. 22 - _____ 2. This cell releases cytokines to activate...Ch. 22 - _____ 3. This cell is activated by binding...Ch. 22 - _____ 4. These two cells destroy an infected cell...Ch. 22 - _____ 5. All of the following are functions of...Ch. 22 - _____ 6. The four characteristics of adaptive...Ch. 22 - _____ 7. During which process does additional...Ch. 22 - _____ 8. This chemical is released by...Ch. 22 - _____ 9. The correct sequence of the major events...Ch. 22 - _____ 10. Two of the major actions of complement...Ch. 22 - Compare the general characteristics of innate...Ch. 22 - Define the inflammatory response, and explain its...Ch. 22 - Describe an antigen.Ch. 22 - Describe class I and class II MHC molecules, and...Ch. 22 - Prob. 15DYKBCh. 22 - Prob. 16DYKBCh. 22 - Explain the general function of cytotoxic...Ch. 22 - Describe both the function of antibodies and...Ch. 22 - There are two branches of adaptive immunity:...Ch. 22 - Prob. 20DYKBCh. 22 - Prob. 1CALCh. 22 - Prob. 2CALCh. 22 - Prob. 3CALCh. 22 - Prob. 4CALCh. 22 - Prob. 5CALCh. 22 - Prob. 1CSLCh. 22 - Prob. 2CSLCh. 22 - Prob. 3CSL
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- What is the function of MHC? Which cells make MHC I, and which make MHC II? What WBCs can present antigens in MHC II?arrow_forwardGenerally speaking, what kinds of cells express MHC I, MHC II, or both? What is presented on MHC I and II, and what kind of T cell recognizes each one? What response occurs when a T cell recognizes what is being presented on MHC I? What happens if it recognizes MHC II? Give an example of each type of recognition.arrow_forwardHow is the newly emerging repertoire of T cells, with their diverse pre-TCRs, further differentiated so that a productive interaction with self-MHC–peptide complexes can occur?arrow_forward
- Why is the concentration of this ligand for the NK-cell receptor CD94:NKG2A. on the target cell an effective measure of the presence or absence of classical MHC class I molecules?arrow_forwardCould a TC cell induce apoptosis in a “self” cell that lost the ability to produce MHC class I molecules?arrow_forwardMajor histocompatibility proteins (MHC) presented with an antigen: are recognized by T lymphocytes both may be expressed by any nucleated cell and are recognized by T lymphocytes both may be expressed by any nucleated cell and are recognized by B lymphocytes may be expressed by any nucleated cell are recognized by B lymphocytesarrow_forward
- What distinguishes MHC I from MHC II? a-aquisition of antigenic peptide in the cytoplasm b-cross-presentation of antigegn to CD4 T cells c- presentation of peptides to the T cell receptor d-binding of a B-amino acid peptide e- presentation of antigenic peptides to CD4 T cellsarrow_forwardMHC class I molecules present peptide antigens derived from a(n) _______ compartment, whereas MHC class II molecules present peptide antigens derived from a(n) _______ compartment: a. extracellular; intracellular b. intracellular; extracellular c. opsonization; neutralization d. neutralization; opsonization e. none of the above.arrow_forwardWhat is the appropriate response when antigen is presented on MHC class II molecules?a) An effector CD8 cell should kill the presenting cell.b) An effector CD4 cell should kill the presenting cell.c) An effector CD8 cell should activate the presenting cell.d) An effector CD4 cell should activate the presenting cell.arrow_forward
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