Concept explainers
(a)
Interpretation: The product obtained by the treatment of given compound with LDA, followed by
Concept introduction: Alkylation of
(b)
Interpretation: The product obtained by the treatment of given compound with LDA, followed by
Concept introduction: Alkylation of aldehydes and ketones takes place in the presence of a strong base. The use of appropriate base, solvent and temperature can yield one major product regioselectively.
(c)
Interpretation: The product obtained by the treatment of given compound with LDA, followed by
Concept introduction: Alkylation of aldehydes and ketones takes place in the presence of a strong base. The use of appropriate base, solvent and temperature can yield one major product regioselectively.
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Organic Chemistry
- (a) Give an acceptable name for compound A. (b) Draw the organic products formed when A is treated with each reagent: [1] H3O+; [2] −OH, H2O; [3] CH3CH2CH2MgBr (excess), then H2O; [4] LiAlH4, then H2O.arrow_forwardDraw a stepwise mechanism for the following reaction and explain the stereochemistry of the product.arrow_forwardDraw the product(s) formed when A is treated with each reagent. (a) NaBH4, CH3OH (b) [1] LiAlH4; [2] H2O (c) CH3CH2MgBr; [2] H2Oarrow_forward
- Dimethyl cyclopropanes can be prepared by the reaction of an α,β-unsaturated carbonyl compound X with two equivalents of a Wittig reagent Y. Draw a stepwise mechanism for this reaction.arrow_forwardDimethyl cyclopropanes can be prepared by the reaction of an α, β- unsaturated carbonyl compound X with two equivalents of a Wittig reagent Y. Draw a stepwise mechanism for this reaction.arrow_forwardDraw the six products (including stereoisomers) formed when A is treated with NBS + hv.arrow_forward
- (a) Give an acceptable name for each compound, (b) Draw the organic products formed when A or B is treated with each reagent: [1] H3O+; [2] −OH, H2O; [3] CH3CH2CH2MgBr (excess), then H2O; [4] LiAlH4, then H2O.arrow_forwardDraw the products formed when A is treated with NBS + hv.arrow_forwardDimethyl cyclopropanes can be prepared by the reaction of an α, β-unsaturated carbonyl compound X with two equivalents of a Wittigreagent Y. Draw a stepwise mechanism for this reaction.arrow_forward
- When A is treated with aqueous −OH, the major product is compound B, which undergoes ester hydrolysis and decarboxylation to form C. Draw a stepwise mechanism for the conversion of A to B.arrow_forwardWhat product is formed when a solution of A and B is treated with mild base? This reaction is the rst step in the synthesis of rosuvastatin (sold as a calcium salt under the trade name Crestor), a drug used to treat patients with high cholesterol.arrow_forwardβ-D-Glucose, a hemiacetal, can be converted to a mixture of acetals on treatment with CH3OH in the presence of acid. Draw a stepwise mechanism for this reaction. Explain why two acetals are formed from a single starting material.arrow_forward
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