OPENINTRO:STATISTICS
4th Edition
ISBN: 9781943450077
Author: OPENINTRO
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Chapter 2.3, Problem 25E
(a)
To determine
Delineate the statement as true or false.
Explain the reasoning, if the statement is identified as false.
(b)
To determine
Obtain the proportion of all patients who have cardiovascular diseases.
(c)
To determine
Find the number of patients in the rosiglitazone group who would be expected to have had cardiovascular problems.
(d)
To determine
i. State the claim being tested.
ii. Identify the group that would provide more support from the alternative hypothesis, more or fewer patients with cardiovascular problems in the rosiglitazone group.
iii. Discuss the suggestion provided by the simulation results about the relationship between taking rosiglitazone and having cardiovascular problems in diabetic patients.
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Side effects of Avandia - Rosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to an
increased risk of serious cardiovascular problems such as stroke, heart failure, and death. A common alternative treatment is pioglitazone, the active
ingredient in a diabetes medicine called Actos. In a nationwide retrospective observational study of 227,571 Medicare beneficiaries aged 65 years or
older, it was found that 2,593 of the 67,593 patients using rosiglitazone and 5,386 of the 159,978 using pioglitazone had serious cardiovascular
problems. The data is summarized in the contingency table below.
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No
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65,000
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154,592
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7,979
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227,571
1. What proportion of all patients had cardiovascular problems? Round your answer to four decimal places.
2. What is the difference in proportion of patients with cardiovascular problems between the…
Although arsenic is known to be a poison, it also has some beneficial medicinal uses. In one study of the use of arsenic to treat acute promyelocytic leukemia (APL), a rare type if blood cancer, APL patients were given an arsenic compound as part of their treatment. Of those receiving arsenic, 32% were in remission and showed no signs of leukemia in subsequent examination. It is known that 18% of APL patients go into remission after conventional treatment. Suppose that the study had included 100 randomly selected patients. Is there sufficient evidence to conclude that the proportion in remission for the arsenic treatment is greater than 0.18, the remission proportion for conventional treatment?
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Rosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to an increased risk of serious cardiovascular problems such as
stroke, heart failure, and death. A common alternative treatment is pioglitazone, the active ingredient in a diabetes medicine called Actos. In a nationwide retrospective
observational study of 227,571 Medicare beneficiaries aged 65 years or older, it was found that 2,593 of the 67,593 patients using rosiglitazone and 5,386 of the 159.978 using
pioglitazone had serious cardiovascular problems. These data are summarized in the contingency table below.
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False
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65,000
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Determine if the following statements is true or false.
Be careful: The reasoning may be wrong even if the statement's conclusion is correct. In such cases, the statement should be considered false.
Total
67,593
159,978
227,571
True or False:…
Chapter 2 Solutions
OPENINTRO:STATISTICS
Ch. 2.1 - Prob. 2GPCh. 2.1 - Prob. 3GPCh. 2.1 - Prob. 4GPCh. 2.1 - Prob. 5GPCh. 2.1 - Prob. 9GPCh. 2.1 - Prob. 10GPCh. 2.1 - Prob. 12GPCh. 2.1 - Prob. 13GPCh. 2.1 - Prob. 15GPCh. 2.1 - Prob. 16GP
Ch. 2.1 - Prob. 17GPCh. 2.1 - Prob. 19GPCh. 2.1 - Prob. 22GPCh. 2.1 - Prob. 1ECh. 2.1 - Prob. 2ECh. 2.1 - Prob. 3ECh. 2.1 - Prob. 4ECh. 2.1 - Prob. 5ECh. 2.1 - Prob. 6ECh. 2.1 - Prob. 7ECh. 2.1 - Prob. 8ECh. 2.1 - Prob. 9ECh. 2.1 - Prob. 10ECh. 2.1 - Prob. 11ECh. 2.1 - Prob. 12ECh. 2.1 - Prob. 13ECh. 2.1 - Prob. 14ECh. 2.1 - Prob. 15ECh. 2.1 - Prob. 16ECh. 2.1 - Prob. 17ECh. 2.1 - Prob. 18ECh. 2.1 - Prob. 19ECh. 2.1 - Prob. 20ECh. 2.2 - Prob. 23GPCh. 2.2 - Prob. 24GPCh. 2.2 - Prob. 28GPCh. 2.2 - Prob. 29GPCh. 2.2 - Prob. 21ECh. 2.2 - Prob. 22ECh. 2.2 - Prob. 23ECh. 2.2 - Prob. 24ECh. 2.3 - Prob. 31GPCh. 2.3 - Prob. 32GPCh. 2.3 - Prob. 34GPCh. 2.3 - Prob. 25ECh. 2.3 - Prob. 26ECh. 2 - Prob. 27CECh. 2 - Prob. 28CECh. 2 - Prob. 29CECh. 2 - Prob. 30CECh. 2 - Prob. 31CECh. 2 - Prob. 32CECh. 2 - Prob. 33CECh. 2 - Prob. 34CE
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- Tan/ page Rosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to an increased risk of serious cardiovascular problems such as stroke, heart failure, and death. A common alternative treatment is pioglitazone, the active ingredient in a diabetes medicine called Actos. In a nationwide retrospective observational study of 227,571 Medicare beneficiaries aged 65 years or older, it was found that 2,593 of the 67,593 patients using rosiglitazone and 5,386 of the 159,978 using pioglitazone had serious cardiovascular problems. These data are summarized in the contingency table below. Cardiovascular problems Yes No Total Rosiglitazone 2,593 65,000 Pioglitazone 5,386 154,592 159,978 67,593 Total 7,979 219,592 227,571 a) Write a set of hypotheses comparing the rates for cardiovascular problems for the two treatments. Но: р, — рp? На: р, — Рp ? Compute the point estimate, the observed difference in rates for cardiovascular problems in the…arrow_forwardRosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to an increased risk of serious cardiovascular problems such as stroke, heart failure, and death. A common alternative treatment is Pioglitazone, the active ingredient in a diabetes medicine called Actos. In a nationwide retrospective observational study of 227,571 Medicare beneficiaries aged 65 years or older, it was found that 2,593 of the 67,593 patients using Rosiglitazone and 5,386 of the 159,978 using Pioglitazone had serious cardiovascular problems. These data are summarized in the contingency table below. Yes No Total Rosiglitazone 2,593 65,000 67,593 5,386 154,592 159,978 7,979 219,592 227,571 Pioglitazone Total a) What proportion of patients using Rosiglitazone had cardiovascular problems? b) What proportion of patients using Pioglitazone had cardiovascular problems? c) What is the point estimate for the difference of proportions of serious cardiovascular problems…arrow_forwardRosiglitazone is the active ingredient in the controversial type 2 diabetes medicine Avandia and has been linked to an increased risk of serious cardiovascular problems such as stroke, heart failure, and death. A common alternative treatment is pioglitazone, the active ingredient in a diabetes medicine called Actos. In a nationwide retrospective observational study of 22,757 Medicare beneficiaries aged 65 years or older, it was found that 259 of the 6,759 patients using rosiglitazone and 539 of the 15,998 using pioglitazone had serious cardiovascular problems. These data are summarized in the contingency table below. Rosiglitazone Pioglitazone Total Cardiovascular problems Yes No 259 539 a) Write a set of hypotheses comparing the rates for cardiovascular problems for the two treatments. Ho: Pr-Pp ? 8 HA: P-Pp? B Total 6,500 6,759 15,459 15,998 798 21,959 22,757 b) Compute the point estimate, the observed difference in rates for cardiovascular problems in the two treatments. Pr-Pp= c)…arrow_forward
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