Brock Biology of Microorganisms, Books a la Carte Edition (14th Edition)
14th Edition
ISBN: 9780321928351
Author: MADIGAN, Michael T., Martinko, John M., Brock, Thomas, Bender, Kelly S., BUCKLEY, Daniel H., Stahl, David A.
Publisher: PEARSON
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Textbook Question
Chapter 23, Problem 2AQ
Coagulase is a virulence factor for Staphylococcus aureus that acts by causing clot formation at the site of S. aureus growth. Streptokinase is a virulence factor for Streptococcus pyogenes that acts by dissolving clots at the site of S. pyogenes growth. Reconcile these opposing strategies for enhancing pathogenicity.
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Below are a list of virulence factors/ strategies paired with an example of an organism that utilizes them. How do each of the following strategies contribute to the virulence of the pathogen?
Strategy - Causes the host to produce more receptors (Organism - Rhinovirus)
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Strategy - Produces a capsule (organism - Klebsiella pneumonia)
Strategy - Ability to move between adjacent cells (organism - Cytomegalovirus)Â
Strategy - Ability to use pilus as a motility structure (organism - Pseudomonas aerogenosa)
Discuss the following virulence factors: collagenase, hemolysin, siderophore. For each, explain the molecules involved, the pathogen-host interaction, and name a species and disease associated with each factor.
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Chapter 23 Solutions
Brock Biology of Microorganisms, Books a la Carte Edition (14th Edition)
Ch. 23.1 - Prob. 1MQCh. 23.1 - Prob. 2MQCh. 23.2 - Prob. 1MQCh. 23.2 - Prob. 2MQCh. 23.3 - Prob. 1MQCh. 23.3 - Identify the major microbes that predominate in...Ch. 23.4 - Prob. 1MQCh. 23.4 - Prob. 2MQCh. 23.5 - Prob. 1MQCh. 23.5 - Prob. 2MQ
Ch. 23.6 - Prob. 1MQCh. 23.6 - Prob. 2MQCh. 23.7 - Prob. 1MQCh. 23.7 - MINIQUIZ
• How do Opa proteins on Neisseria...Ch. 23.8 - Prob. 1MQCh. 23.8 - Prob. 2MQCh. 23.9 - What key features are shared by all AB exotoxins?Ch. 23.9 - Prob. 2MQCh. 23.10 - Prob. 1MQCh. 23.10 - Why is it necessary to test for endotoxin in water...Ch. 23.11 - Prob. 1MQCh. 23.11 - Prob. 2MQCh. 23.12 - Prob. 1MQCh. 23.12 - Prob. 2MQCh. 23 - Prob. 1RQCh. 23 - Prob. 2RQCh. 23 - Prob. 3RQCh. 23 - Prob. 4RQCh. 23 - REVIEW QUESTIONS
5. Describe the relationship...Ch. 23 - Prob. 6RQCh. 23 - Prob. 7RQCh. 23 - Prob. 8RQCh. 23 - QDistinguish between the mechanism of cytotoxins...Ch. 23 - Prob. 10RQCh. 23 - Prob. 11RQCh. 23 - REVIEW QUESTIONS
12. Identify common factors that...Ch. 23 - APPLICATION QUESTIONS
1. Mucous membranes are...Ch. 23 - Coagulase is a virulence factor for Staphylococcus...Ch. 23 - Although mutants incapable of producing exotoxins...
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- Compare and contrast the virulence factors associated with Staphylococcus aureus and Streptococcus pyogenes. Which of these agents is the most difficult to treat. Explain your answerarrow_forwardGiven that there is currently no cure for mad cow disease, what is likely to be the most effective action to reduce its transmission?arrow_forwardAs an illustration, a patient undergoing a laparoscopic-assisted vaginal hysterectomy (LAVH) procedure under general anesthesia might be happier not to know the numbers of portals of entry for potential transmission of pathogenic microbes to which she will be subjected. The anesthesia provider would be accessing the patients airway and vascular system by an IV line. Which portals of entry will the surgeon be accessing?arrow_forward
- Before development of a vaccine against this microbe, thedisease it caused accounted for two-thirds of bacterial meningi-tis cases during the first year of life but is still the number oneleading cause of mental retardation in patients who survive seri-ous disease due to permanent central nervous system disorders.What is the microorganism?(a) Haemophilus influenzae type B(b) Haemophilus influenzae type A(c) Neisseria meningitidis(d) Streptococcus pneumoniae(e) Listeria monocytogenesarrow_forwardName the metabolic end products that can facilitate the spread ofstreptococci and initiate secondary sites of streptococcal infection.arrow_forwardHow does Mycobacterium tuberculosis gain access through that preferred portal of entry Explain how the Mycobacterium tuberculosis is able to evade innate human host defenses that prevent this from occurring. discuss specific components of your pathogen. (Examples may include capsules, cell wall components, exoenzymes, antigenic variation and penetration of the host cell cytoskeleton.)arrow_forward
- A child presents with yellow crusting lesions on the arms and legs. It is determined that this is being caused by Streptococcus pyogenes. In what ways is the organism Streptococcus pyogenes different from Staphylococcus aureus?arrow_forwardWhat are the mitigating measures to prevent the escalation of the black Sigatoka disease? Explain.arrow_forwardKlebsiella Pneumoniae produces a capsule: How does klebsiella pneumonia contribute to the virulence of the pathogen?arrow_forward
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